Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.31 |
| ▸ | PRKCG | P05129 | 2/20 | 0.31 |
| ▸ | PRKCB | P05771 | 2/20 | 0.31 |
| ▸ | PRKCA | P17252 | 2/20 | 0.31 |
| ▸ | PRKCH | P24723 | 2/20 | 0.31 |
| ▸ | PRKCI | P41743 | 2/20 | 0.31 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.31 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.31 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.31 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.31 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15032837 | 0.93 | LMNA (0.50) | LMNAPKMHSD17B10CES1PRKD3 | |
| SCHEMBL17853915 | 0.92 | LMNA (0.42) | LMNAPKMHSD17B10 | |
| SCHEMBL9067103 | 0.91 | LMNA (0.53) | LMNAHSD17B10CES1PRKD3PRKCG | |
| SCHEMBL28550544 | 0.91 | LMNA (0.53) | LMNAHSD17B10CES1PRKD3PRKCG | |
| SCHEMBL29240698 | 0.91 | LMNA (0.53) | LMNAHSD17B10CES1PRKD3PRKCG | |
| SCHEMBL12305456 | 0.91 | LMNA (0.42) | LMNA | |
| SCHEMBL113935 | 0.91 | LMNA (0.39) | LMNA | |
| SCHEMBL9067248 | 0.86 | LMNA (0.36) | LMNA | |
| SCHEMBL11772944 | 0.84 | LMNA (0.39) | LMNA | |
| SCHEMBL12761201 | 0.83 | LMNA (0.44) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110511672-B | Bottom-coating active siloxane composition and preparation method and application thereof | 广东普赛达密封粘胶有限公司 | 2021-05-04 | — | — | CN | disclosed |
| EP-0033517-B1 | PROCESS FOR PREPARING SULFUR CONTAINING POLYSILOXANE POLYMERS, THE PRODUCTS OBTAINED THEREBY AND THE USE OF THE PRODUCTS AS CROSS-LINKING AGENTS | SWS Silicones Corporation (US) | 1985-08-21 | — | — | EP | disclosed |
| US-4289867-A | Organofunctional polysiloxane polymers and a method for preparing the same | SWS SILICONES CORPORATION (US) | 1981-09-15 | — | — | US | disclosed |
| EP-0034191-A1 | Process for preparing thiofunctional polysiloxane polymers and products obtained thereby | SWS Silicones Corporation (US) | 1981-08-26 | — | — | EP | disclosed |
| EP-0033517-A1 | Process for preparing sulfur containing polysiloxane polymers, the products obtained thereby and the use of the products as cross-linking agents | SWS Silicones Corporation (US) | 1981-08-12 | — | — | EP | disclosed |
| US-4230816-A | Thiofunctional polysiloxane polymers | SWS SILICONES CORPORATION (US) | 1980-10-28 | — | — | US | disclosed |
| US-4046795-A | Process for preparing thiofunctional polysiloxane polymers | SWS SILICONES CORPORATION (US) | 1977-09-06 | — | — | US | disclosed |