SCHEMBL1102558

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1103633	0.89	MAPK10 (0.42)	KDM4EHTTPOLBRAD52PARP1
	SCHEMBL1102677	0.82	TNF (0.47)	KDM4EHTTPOLBRAD52PARP1
	SCHEMBL1102900	0.82	TNF (0.47)	KDM4EHTTPOLBRAD52PARP1
	SCHEMBL1102798	0.82	TNF (0.47)	KDM4EHTTPOLBRAD52PARP1
	SCHEMBL1102806	0.82	TNF (0.47)	KDM4EHTTPOLBRAD52PARP1
	SCHEMBL1103619	0.82	MAPK10 (0.45)	CYP11B1MAPK10TNFCSNK2A2CSNK2B
	SCHEMBL1102635	0.82	CYP11B1 (0.54)	KDM4EHTTPOLBRAD52TDO2
	SCHEMBL1102639	0.82	TNF (0.45)	KDM4EHTTPOLBRAD52TDO2
	SCHEMBL1102481	0.82	CYP11B1 (0.54)	KDM4EHTTPOLBRAD52TDO2
	SCHEMBL1103635	0.82	CYP11B2 (0.54)	TDO2CYP11B1MAPK10CYP17A1CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.