SCHEMBL11026124

SCHEMBL11026124

C/C=C(\C)C(=O)/C(C)=C/C

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.39
TSHR P16473 1/20 0.36
THPO P40225 1/20 0.36
FFAR3 O14843 1/20 0.36
LCK P06239 1/20 0.36
FYN P06241 1/20 0.36
ALDH1A1 P00352 1/20 0.35
NFKB1 P19838 1/20 0.35
TRPA1 O75762 1/20 0.35
CA1 P00915 2/20 0.33
ALOX15 P16050 1/20 0.33
BLM P54132 1/20 0.33
PMP22 Q01453 1/20 0.33
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL276990 1.00 LMNA (0.39) LMNATSHRTHPOFFAR3LCK
SCHEMBL756363 1.00 LMNA (0.39) LMNATSHRTHPOFFAR3LCK
SCHEMBL4402822 0.92 FFAR3 (0.46) LMNATSHRTHPOFFAR3LCK
SCHEMBL5081251 0.82
SCHEMBL6024436 0.82
SCHEMBL3461461 0.82
SCHEMBL18424470 0.80
SCHEMBL18424468 0.80
SCHEMBL11586713 0.79
SCHEMBL2737851 0.79 FFAR3 (0.35) FFAR3LCKFYNMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0040603-B1 OPTICAL FILTERING ELEMENT MUELLER, Gary E. (US) 1985-01-23 EP claimed
US-4320940-A Optical filtering element MUELLER GARY E 1982-03-23 US claimed
US-4320939-A Optical filtering element including fluorescent material MUELLER GARY E 1982-03-23 US claimed
EP-0040603-A4 OPTICAL FILTERING ELEMENT. MUELLER GARY E (US) 1982-02-16 EP claimed
EP-0040603-A1 OPTICAL FILTERING ELEMENT. MUELLER GARY E (US) 1981-12-02 EP claimed
WO-1981000769-A1 OPTICAL FILTERING ELEMENT MUELLER G 1981-03-19 WO claimed
EP-0040603-B1 OPTICAL FILTERING ELEMENT MUELLER, Gary E. (US) 1985-01-23 EP disclosed
US-4320940-A Optical filtering element MUELLER GARY E 1982-03-23 US disclosed
US-4320939-A Optical filtering element including fluorescent material MUELLER GARY E 1982-03-23 US disclosed
EP-0040603-A4 OPTICAL FILTERING ELEMENT. MUELLER GARY E (US) 1982-02-16 EP disclosed
EP-0040603-A1 OPTICAL FILTERING ELEMENT. MUELLER GARY E (US) 1981-12-02 EP disclosed
WO-1981000769-A1 OPTICAL FILTERING ELEMENT MUELLER G 1981-03-19 WO disclosed