Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11026362 | 1.00 | POLB (0.47) | POLBEPHX2MEN1KMT2AL3MBTL1 | |
| SCHEMBL11032560 | 0.89 | POLB (0.45) | POLBEPHX2MEN1KMT2AL3MBTL1 | |
| SCHEMBL11032561 | 0.89 | POLB (0.45) | POLBEPHX2MEN1KMT2AL3MBTL1 | |
| SCHEMBL11032563 | 0.89 | POLB (0.45) | POLBEPHX2MEN1KMT2AL3MBTL1 | |
| SCHEMBL11271759 | 0.88 | POLB (0.44) | POLBEPHX2MEN1KMT2AL3MBTL1 | |
| SCHEMBL11058256 | 0.88 | POLB (0.44) | POLBEPHX2MEN1KMT2AL3MBTL1 | |
| SCHEMBL11022850 | 0.82 | NAAA (0.49) | GAA | |
| SCHEMBL11022846 | 0.82 | NAAA (0.49) | GAA | |
| SCHEMBL9781786 | 0.80 | POLB (0.51) | POLBEPHX2MEN1KMT2AL3MBTL1 | |
| SCHEMBL9781780 | 0.80 | POLB (0.51) | POLBEPHX2MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0061765-B1 | BETA-LACTAMS | E.R. SQUIBB & SONS, INC. (US) | 1985-08-28 | — | — | EP | disclosed |
| US-4478749-A | AMINO ACID DERTIVATIVES ANTIBIOTICS | E. R. SQUIBB & SONS, INC. (US) | 1984-10-23 | — | — | US | disclosed |
| EP-0061765-A1 | Beta-Lactams | E.R. SQUIBB & SONS, INC. (US) | 1982-10-06 | — | — | EP | disclosed |