SCHEMBL11026596

SCHEMBL11026596

Cc1ccc2[c]c3cc(C)ccc3[c]c2c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 3/20 0.43
CYP1A2 P05177 3/20 0.43
TDP1 Q9NUW8 5/20 0.39
ACHE P22303 3/20 0.39
TP53 P04637 3/20 0.38
ALOX15 P16050 3/20 0.38
CYP3A4 P08684 2/20 0.38
THRB P10828 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
TRPA1 O75762 1/20 0.38
ALDH1A1 P00352 3/20 0.36
HSD17B10 Q99714 3/20 0.33
KDM4E B2RXH2 2/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
LMNA P02545 2/20 0.33
GAA P10253 2/20 0.33
HPGD P15428 2/20 0.33
NOS3 P29474 1/20 0.33
NOS1 P29475 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1263751 0.92 TDP1 (0.42) CYP2A6CYP1A2TDP1ACHETP53
SCHEMBL11025889 0.88 CYP3A4 (0.37) CYP2A6CYP1A2TP53CYP3A4SMN1; SMN2
SCHEMBL11028225 0.88 CYP3A4 (0.37) CYP2A6CYP1A2TP53CYP3A4SMN1; SMN2
SCHEMBL820190 0.78 CYP2A6 (0.52) CYP2A6CYP1A2TDP1ACHETP53
SCHEMBL819377 0.76 CYP2A6 (0.50) CYP2A6CYP1A2TDP1ALDH1A1HSD17B10
SCHEMBL2250860 0.72 CYP1A2 (0.39) CYP2A6CYP1A2TDP1ACHETP53
SCHEMBL2885652 0.70 CYP2A6 (0.38) CYP2A6CYP1A2TDP1ACHETP53
SCHEMBL593462 0.69 CYP2A6 (0.48) CYP2A6CYP1A2TDP1ACHETP53
SCHEMBL667256 0.67 CYP1A2 (0.52) CYP2A6CYP1A2TDP1TP53ALDH1A1
SCHEMBL11030089 0.67 TP53 (0.43) CYP2A6TDP1TP53ALOX15CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0053937-B1 POLYNUCLEAR FUSED AROMATIC RING TYPE POLYMER AND PREPARATION THEREOF Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1985-06-19 EP claimed
US-4463162-A POLYESTERS FROM ANTHRACENEDIOL ASAHI-DOW LIMITED (JP) 1984-07-31 US claimed
EP-0053937-A1 Polynuclear fused aromatic ring type polymer and preparation thereof Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1982-06-16 EP claimed
EP-0053937-B1 POLYNUCLEAR FUSED AROMATIC RING TYPE POLYMER AND PREPARATION THEREOF Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1985-06-19 EP disclosed
US-4463162-A POLYESTERS FROM ANTHRACENEDIOL ASAHI-DOW LIMITED (JP) 1984-07-31 US disclosed
EP-0053937-A1 Polynuclear fused aromatic ring type polymer and preparation thereof Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1982-06-16 EP disclosed