SCHEMBL667256

SCHEMBL667256

Cc1[c]c2ccc(C)cc2cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 6/20 0.52
CYP2A6 P11509 5/20 0.52
TDP1 Q9NUW8 2/20 0.44
ALDH1A1 P00352 4/20 0.36
NCK1 P16333 1/20 0.36
BACE1 P56817 1/20 0.36
KDM4E B2RXH2 1/20 0.36
LMNA P02545 1/20 0.36
GAA P10253 1/20 0.36
HPGD P15428 1/20 0.36
HSD17B10 Q99714 1/20 0.36
CA12 O43570 3/20 0.35
CA9 Q16790 3/20 0.35
TP53 P04637 1/20 0.34
MAPT P10636 1/20 0.34
RXFP1 Q9HBX9 1/20 0.34
CCR1 P32246 1/20 0.32
CCR5 P51681 1/20 0.32
CCR8 P51685 1/20 0.32
NQO2 P16083 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL593462 0.84 CYP2A6 (0.48) CYP1A2CYP2A6TDP1ALDH1A1NCK1
SCHEMBL819377 0.80 CYP2A6 (0.50) CYP1A2CYP2A6TDP1ALDH1A1NCK1
SCHEMBL9031406 0.80 CYP2A6 (0.43) CYP2A6ALDH1A1KDM4EHSD17B10TP53
SCHEMBL18207370 0.78 CYP1A2 (0.48) CYP1A2CYP2A6TDP1ALDH1A1NCK1
SCHEMBL819816 0.74 CYP2A6 (0.52) CYP1A2CYP2A6TDP1ALDH1A1KDM4E
SCHEMBL820190 0.73 CYP2A6 (0.52) CYP1A2CYP2A6TDP1ALDH1A1NCK1
SCHEMBL65563 0.71 CYP2A6 (0.37) CYP1A2CYP2A6TDP1ALDH1A1HPGD
SCHEMBL5693005 0.71 CYP2A6 (0.37) CYP1A2CYP2A6TDP1ALDH1A1HPGD
SCHEMBL1462974 0.71 CYP2A6 (0.43) CYP1A2CYP2A6TDP1ALDH1A1NCK1
SCHEMBL328771 0.71 CYP2A6 (0.43) CYP1A2CYP2A6TDP1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 188 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101987822-A Organic electroluminescent material and application thereof BEIJING VISIONOX TECHNOLOGY CO 2011-03-23 CN claimed
US-11681222-B2 Fluorine-containing polymer, purification method, and radiation-sensitive resin composition JSR CORPORATION (JP) 2023-06-20 US disclosed
US-20220137508-A9 FLUORINE-CONTAINING POLYMER, PURIFICATION METHOD, AND RADIATION-SENSITIVE RESIN COMPOSITION JSR CORPORATION (JP) 2022-05-05 US disclosed
US-20210278764-A1 FLUORINE-CONTAINING POLYMER, PURIFICATION METHOD, AND RADIATION-SENSITIVE RESIN COMPOSITION JSR CORPORATION (JP) 2021-09-09 US disclosed
US-11036133-B2 Fluorine-containing polymer, purification method, and radiation-sensitive resin composition JSR CORPORATION (JP) 2021-06-15 US disclosed
US-20200124961-A1 FLUORINE-CONTAINING POLYMER, PURIFICATION METHOD, AND RADIATION-SENSITIVE RESIN COMPOSITION JSR CORPORATION (JP) 2020-04-23 US disclosed
US-10620534-B2 Fluorine-containing polymer, purification method, and radiation-sensitive resin composition JSR CORPORATION (JP) 2020-04-14 US disclosed
US-20190278175-A9 FLUORINE-CONTAINING POLYMER, PURIFICATION METHOD, AND RADIATION-SENSITIVE RESIN COMPOSITION JSR CORPORATION (JP) 2019-09-12 US disclosed
EP-2743249-B1 CYCLIC COMPOUND, METHOD FOR PRODUCING SAME, COMPOSITION, AND METHOD FOR FORMING RESIST PATTERN MITSUBISHI GAS CHEMICAL CO (JP) 2019-07-24 EP disclosed
EP-2911002-B1 RESIST COMPOSITION MITSUBISHI GAS CHEMICAL CO (JP) 2019-07-17 EP disclosed
US-4965006-A N-substituted tetrahydroquinolines for use as antioxidants in lubricants CIBA-GEIGY CORPORATION (US) 1990-10-23 US disclosed
US-4929732-A N-substituted tetrahydroquinolines for use as antioxidants in lubricants CIBA-GEIGY CORPORATION (US) 1990-05-29 US disclosed
US-4919832-A HYDRAULIC OIL OR METAL WORKING FLUID CIBA-GEIGY CORPORATION (US) 1990-04-24 US disclosed
US-4906722-A Thermosetting reactive systems CIBA-GEIGY CORPORATION (US) 1990-03-06 US disclosed
EP-0319473-A2 Heat-curable reactive systems CIBA-GEIGY AG (CH) 1989-06-07 EP disclosed
US-4828741-A N-substituted tetrahydroquinolines for use as antioxidants in lubricants CIBA-GEIGY CORPORATION (US) 1989-05-09 US disclosed
EP-0273868-A2 N-substituted tetrahydroquinolines as antioxidants for lubricants CIBA-GEIGY AG (CH) 1988-07-06 EP disclosed
US-4654363-A Synthetic analogs of mevinolin MERCK & CO., INC. (US) 1987-03-31 US disclosed
US-4420437-A Preparation of a 2-aralkyl-5,5-dialkyl-1,3,2-dioxaphosphorinan-2-one from 2-aralkoxy-5,5-dialkyl-1,3,2-dioxaphosphorinane WITCO CHEMICAL CORPORATION (US) 1983-12-13 US disclosed
US-3993684-A PHOTOSENSITIVE ACRYLIC ESTER POLYMERS WESTERN LITHO PLATE & SUPPLY CO. (US) 1976-11-23 US disclosed