Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 4/20 | 0.70 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.70 |
| ▸ | SRC | P12931 | 2/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.70 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.70 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.70 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.70 |
| ▸ | LDHA | P00338 | 1/20 | 0.70 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.70 |
| ▸ | FBP1 | P09467 | 1/20 | 0.70 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.70 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.70 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.70 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.70 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.70 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.70 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.70 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.70 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.70 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30969941 | 1.00 | P2RY1 (0.70) | P2RY1P2RY2SRCSMN1; SMN2DNPH1 | |
| SCHEMBL20277526 | 1.00 | P2RY1 (0.70) | P2RY1P2RY2SRCSMN1; SMN2DNPH1 | |
| SCHEMBL15305338 | 1.00 | P2RY1 (0.70) | P2RY1P2RY2SRCSMN1; SMN2DNPH1 | |
| SCHEMBL30558659 | 0.92 | P2RY1 (0.66) | P2RY1P2RY2SRCSMN1; SMN2DNPH1 | |
| SCHEMBL20277545 | 0.92 | ADK (0.67) | P2RY1P2RY2SRCSMN1; SMN2DNPH1 | |
| Tubercidin Triphosphate SCHEMBL12932266 | 0.91 | P2RY1 (0.67) | P2RY1P2RY2SRCSMN1; SMN2TRPM2 | |
| Tubercidin Triphosphate SCHEMBL29357683 | 0.91 | P2RY1 (0.67) | P2RY1P2RY2SRCSMN1; SMN2TRPM2 | |
| SCHEMBL22524124 | 0.91 | P2RY1 (0.61) | P2RY1P2RY2SRCSMN1; SMN2DNPH1 | |
| SCHEMBL14853624 | 0.88 | P2RY1 (0.65) | P2RY1P2RY2SRCSMN1; SMN2TRPM2 | |
| Tubercidin SCHEMBL9239366 | 0.86 | ADK (0.73) | SMN1; SMN2ADORA1ADKPRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4352795-A | 7-β-D-Arabinofuranosyl-7H-pyrrolo[2,3-d]pyrimidine compounds and methods for their production | WARNER-LAMBERT COMPANY (US) | 1982-10-05 | — | — | US | claimed |
| EP-0057548-A2 | 7-Beta-D-arabinofuranosyl-7H-pyrrolo(2,3-d)pyrimidine-4-amine 5'-phosphate compounds useful as antiviral agents, pharmaceutical compositions containing the compounds, and processes for producing the compounds | WARNER-LAMBERT COMPANY (US) | 1982-08-11 | — | — | EP | claimed |
| EP-0057548-B1 | 7-BETA-D-ARABINOFURANOSYL-7H-PYRROLO(2,3-D)PYRIMIDINE-4-AMINE 5'-PHOSPHATE COMPOUNDS USEFUL AS ANTIVIRAL AGENTS, PHARMACEUTICAL COMPOSITIONS CONTAINING THE COMPOUNDS, AND PROCESSES FOR PRODUCING THE COMPOUNDS | WARNER-LAMBERT COMPANY (US) | 1985-07-03 | — | — | EP | disclosed |
| US-4439604-A | 7-β-D-Arabinofuranosyl-7H-pyrrolo[2,3-d]pyrimidine compounds and methods for their production | WARNER-LAMBERT COMPANY (US) | 1984-03-27 | — | — | US | disclosed |
| US-4352795-A | 7-β-D-Arabinofuranosyl-7H-pyrrolo[2,3-d]pyrimidine compounds and methods for their production | WARNER-LAMBERT COMPANY (US) | 1982-10-05 | — | — | US | disclosed |
| EP-0057548-A2 | 7-Beta-D-arabinofuranosyl-7H-pyrrolo(2,3-d)pyrimidine-4-amine 5'-phosphate compounds useful as antiviral agents, pharmaceutical compositions containing the compounds, and processes for producing the compounds | WARNER-LAMBERT COMPANY (US) | 1982-08-11 | — | — | EP | disclosed |
| EP-0057548-A2 | 7-Beta-D-arabinofuranosyl-7H-pyrrolo(2,3-d)pyrimidine-4-amine 5'-phosphate compounds useful as antiviral agents, pharmaceutical compositions containing the compounds, and processes for producing the compounds | WARNER-LAMBERT COMPANY (US) | 1982-08-11 | — | — | EP | disclosed |