Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 12/20 | 0.49 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.47 |
| ▸ | PGR | P06401 | 2/20 | 0.47 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.47 |
| ▸ | SHBG | P04278 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11027165 | 1.00 | AR (0.49) | ARNR3C1PGRNR3C2SHBG | |
| SCHEMBL6708645 | 1.00 | AR (0.49) | ARNR3C1PGRNR3C2SHBG | |
| SCHEMBL10947065 | 0.99 | AR (0.49) | ARNR3C1PGRNR3C2SHBG | |
| SCHEMBL10955541 | 0.99 | AR (0.49) | ARNR3C1PGRNR3C2SHBG | |
| Potassium Ion SCHEMBL10947070 | 0.92 | TDP1 (0.54) | ARNR3C1PGRNR3C2SHBG | |
| Potassium Ion SCHEMBL10955544 | 0.92 | TDP1 (0.54) | ARNR3C1PGRNR3C2SHBG | |
| SCHEMBL10950282 | 0.91 | AR (0.50) | ARNR3C1PGRNR3C2SHBG | |
| SCHEMBL10962358 | 0.90 | NR3C1 (0.45) | ARNR3C1PGRNR3C2SHBG | |
| SCHEMBL11110788 | 0.85 | MEN1 (0.60) | ARSHBGALDH1A1MEN1KMT2A | |
| SCHEMBL11114508 | 0.85 | MEN1 (0.60) | ARSHBGALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0061418-A1 | 7-Alpha-alkoxycarbonyl-15-beta-16-beta-methylene-4 androstene, process for their preparation and their utilization as pharmaceutical preparations | SCHERING AKTIENGESELLSCHAFT (DE) | 1982-09-29 | — | — | EP | claimed |
| EP-0061418-B1 | 7-ALPHA-ALKOXYCARBONYL-15-BETA-16-BETA-METHYLENE-4 ANDROSTENE, PROCESS FOR THEIR PREPARATION AND THEIR UTILIZATION AS PHARMACEUTICAL PREPARATIONS | SCHERING AKTIENGESELLSCHAFT (DE) | 1985-08-21 | — | — | EP | disclosed |
| US-4450107-A | 7α-Alkoxycarbonyl-15β,16β-methylene-4-androstenes, process for the preparation thereof, and use thereof as medicinal agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1984-05-22 | — | — | US | disclosed |
| EP-0061418-A1 | 7-Alpha-alkoxycarbonyl-15-beta-16-beta-methylene-4 androstene, process for their preparation and their utilization as pharmaceutical preparations | SCHERING AKTIENGESELLSCHAFT (DE) | 1982-09-29 | — | — | EP | disclosed |