⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24786249 | 0.82 | — | — | |
| SCHEMBL5670604 | 0.65 | — | — | |
| SCHEMBL31663430 | 0.59 | — | — | |
| SCHEMBL873036 | 0.57 | HDAC8 (0.32) | — | |
| SCHEMBL32659903 | 0.57 | HDAC8 (0.32) | — | |
| SCHEMBL15926079 | 0.55 | EGFR (0.30) | — | |
| SCHEMBL15697860 | 0.55 | — | — | |
| SCHEMBL5831499 | 0.47 | ALDH1A1 (0.36) | — | |
| SCHEMBL45611 | 0.42 | — | — | |
| Hydrochloric Acid SCHEMBL2463652 | 0.40 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8852320-B2 | Preparation of metal-triazolate frameworks | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-10-07 | — | — | US | claimed |
| CN-103429597-A | Preparation of metal-triazolate frameworks | UNIV CALIFORNIA | 2013-12-04 | — | — | CN | claimed |
| EP-2665733-A2 | PREPARATION OF METAL-TRIAZOLATE FRAMEWORKS | The Regents of The University of California (US) | 2013-11-27 | — | — | EP | claimed |
| US-20120186449-A1 | PREPARATION OF METAL-TRIAZOLATE FRAMEWORKS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-07-26 | — | — | US | claimed |
| WO-2012100224-A2 | PREPARATION OF METAL-TRIAZOLATE FRAMEWORKS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-07-26 | — | — | WO | claimed |
| US-11530237-B2 | Compositions and methods for treating CNS disorders | SAGE THERAPEUTICS, INC. (US) | 2022-12-20 | — | — | US | disclosed |
| US-20200392177-A1 | COMPOSITIONS AND METHODS FOR TREATING CNS DISORDERS | SAGE THERAPEUTICS, INC. | 2020-12-17 | — | — | US | disclosed |
| US-20180114925-A1 | FLUORESCENT ORGANIC LIGHT EMITTING ELEMENTS HAVING HIGH EFFICIENCY | UDC IRELAND LTD (IE) | 2018-04-26 | — | — | US | disclosed |
| US-9853224-B2 | Fluorescent organic light emitting elements having high efficiency | UDC IRELAND LIMITED (IE) | 2017-12-26 | — | — | US | disclosed |
| US-20170186976-A1 | Fluorescent Organic Light Emitting Elements Having High Efficiency | UDC IRELAND LIMITED (IE) | 2017-06-29 | — | — | US | disclosed |
| US-8852320-B2 | Preparation of metal-triazolate frameworks | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-10-07 | — | — | US | disclosed |
| CN-103429597-A | Preparation of metal-triazolate frameworks | UNIV CALIFORNIA | 2013-12-04 | — | — | CN | disclosed |
| EP-2665733-A2 | PREPARATION OF METAL-TRIAZOLATE FRAMEWORKS | The Regents of The University of California (US) | 2013-11-27 | — | — | EP | disclosed |
| WO-2012100224-A2 | PREPARATION OF METAL-TRIAZOLATE FRAMEWORKS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-07-26 | — | — | WO | disclosed |
| US-20120186449-A1 | PREPARATION OF METAL-TRIAZOLATE FRAMEWORKS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-07-26 | — | — | US | disclosed |