Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8014862 | 0.83 | ALDH1A1 (0.31) | ALDH1A1KMT2ALMNAMAPTHPGD | |
| SCHEMBL11761722 | 0.81 | ALDH1A1 (0.30) | ALDH1A1KMT2ALMNAMAPTHPGD | |
| SCHEMBL10408073 | 0.79 | — | — | |
| SCHEMBL10407795 | 0.75 | MAPT (0.32) | ALDH1A1KMT2ALMNAMAPTHPGD | |
| SCHEMBL28057644 | 0.72 | ALDH1A1 (0.36) | ALDH1A1KMT2ALMNAMAPTHPGD | |
| SCHEMBL27627751 | 0.71 | ALDH1A1 (0.36) | ALDH1A1KMT2ALMNAMAPTHPGD | |
| SCHEMBL1276543 | 0.70 | ALDH1A1 (0.38) | ALDH1A1KMT2ALMNAMAPTHPGD | |
| SCHEMBL435747 | 0.70 | ALDH1A1 (0.38) | ALDH1A1KMT2ALMNAMAPTHPGD | |
| SCHEMBL1855939 | 0.69 | KMT2A (0.39) | ALDH1A1KMT2ALMNAMAPTHPGD | |
| SCHEMBL8394291 | 0.68 | ALDH1A1 (0.41) | ALDH1A1KMT2ALMNAMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0144573-A2 | Catalyst system for the production of polyurethanes | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1985-06-19 | — | — | EP | disclosed |
| US-4500654-A | N-SUBSTITUTED ALKOXYALKYL PIPERAZINE | ABBOTT LABORATORIES (US) | 1985-02-19 | — | — | US | disclosed |