Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 7/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11027107 | 0.92 | TSHR (0.50) | KCNH2EPHX1TSHRMAOBKCNJ1 | |
| SCHEMBL10397395 | 0.88 | EPHX1 (0.47) | KCNH2EPHX1TSHRPOLBAPEX1 | |
| SCHEMBL8733212 | 0.87 | TSHR (0.55) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL11024327 | 0.86 | TSHR (0.43) | KCNH2EPHX1TSHRPOLBAPEX1 | |
| SCHEMBL18373560 | 0.85 | LMNA (0.50) | KCNH2TSHRHTTTDP1MAOB | |
| SCHEMBL11025492 | 0.84 | MAOB (0.47) | TSHRHTTMAOBRAB9A | |
| SCHEMBL11026197 | 0.83 | TDP1 (0.40) | KCNH2EPHX1TSHRPOLBAPEX1 | |
| SCHEMBL5445040 | 0.82 | MAOB (0.54) | POLBHTTMAOBMAPTRAB9A | |
| SCHEMBL2676535 | 0.82 | TSHR (0.56) | KCNH2EPHX1TSHRKCNJ1 | |
| SCHEMBL713324 | 0.82 | MAPT (0.60) | KCNH2POLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0067954-B1 | ORGANIC PHOTOCONDUCTIVE COMPOSITIONS FOR ELECTROPHOTOGRAPHY | KABUSHIKI KAISHA TOSHIBA (JP) | 1985-08-28 | — | — | EP | claimed |
| EP-0067954-A2 | Organic photoconductive compositions for electrophotography | KABUSHIKI KAISHA TOSHIBA (JP) | 1982-12-29 | — | — | EP | claimed |
| EP-0067954-B1 | ORGANIC PHOTOCONDUCTIVE COMPOSITIONS FOR ELECTROPHOTOGRAPHY | KABUSHIKI KAISHA TOSHIBA (JP) | 1985-08-28 | — | — | EP | disclosed |
| EP-0067954-A2 | Organic photoconductive compositions for electrophotography | KABUSHIKI KAISHA TOSHIBA (JP) | 1982-12-29 | — | — | EP | disclosed |