SCHEMBL11027615

SCHEMBL11027615

C=C(CC(=S)Nc1ccccc1)C(N)=O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.50
HSD17B10 Q99714 3/20 0.50
TP53 P04637 2/20 0.50
TSHR P16473 2/20 0.50
TAS2R38 P59533 2/20 0.50
TYR P14679 1/20 0.50
KDM1A O60341 1/20 0.45
ABAT P80404 1/20 0.45
GAA P10253 5/20 0.44
MAPT P10636 1/20 0.44
GFER P55789 1/20 0.44
EPHX1 P07099 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
CYP3A4 P08684 2/20 0.44
EPHX2 P34913 1/20 0.44
CDK9 P50750 1/20 0.44
CLK4 Q9HAZ1 1/20 0.44
LMNA P02545 1/20 0.43
KMT2A Q03164 1/20 0.42
KDM4E B2RXH2 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5176159 0.82 KDM1A (0.61) TP53TSHRKDM1AGAAMAPT
SCHEMBL3069525 0.82 ALDH1A1 (0.57) ALDH1A1HSD17B10TP53TSHRTAS2R38
SCHEMBL3069527 0.79 ALDH1A1 (0.64) ALDH1A1HSD17B10TP53TSHRTAS2R38
SCHEMBL3071122 0.77 HSD17B10 (0.64) ALDH1A1HSD17B10TP53TSHRTAS2R38
SCHEMBL3071119 0.76 ALDH1A1 (0.58) ALDH1A1HSD17B10TP53TSHRTAS2R38
SCHEMBL3079514 0.74 HSD17B10 (0.57) ALDH1A1HSD17B10TP53TSHRTAS2R38
SCHEMBL3062252 0.74 MAPT (0.58) ALDH1A1HSD17B10TP53TSHRTAS2R38
SCHEMBL3073451 0.74 ALDH1A1 (0.61) ALDH1A1HSD17B10TP53TSHRTAS2R38
SCHEMBL9129270 0.73 KMT2A (0.59) ALDH1A1HSD17B10TP53TSHRTAS2R38
SCHEMBL5761295 0.72 ALDH1A1 (0.58) ALDH1A1HSD17B10TP53TSHRTAS2R38

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4297978-A1 COMPOSITIONS AND METHODS FOR SENSITIZING HEAT MEDIA Solenis Technologies Cayman, L.P. (CH) 2024-01-03 EP disclosed
US-11529819-B2 Recording material and compound NIPPON SODA CO., LTD. (JP) 2022-12-20 US disclosed
EP-4022391-A2 HEAT SENSITIVE RECORDING MATERIAL WITH NON-PHENOLIC COLOR DEVELOPERS Solenis Technologies Cayman, L.P. (KY) 2022-07-06 EP disclosed
US-20210060994-A1 HEAT SENSITIVE RECORDING MATERIAL WITH NON-PHENOLIC COLOR DEVELOPERS BASF SE (DE) 2021-03-04 US disclosed
WO-2021041600-A2 HEAT SENSITIVE RECORDING MATERIAL WITH NON-PHENOLIC COLOR DEVELOPERS SOLENIS TECHNOLOGIES CAYMAN, L.P. (KY) 2021-03-04 WO disclosed
EP-3254860-B1 RECORDING MATERIAL AND RECORDING SHEET NIPPON SODA CO (JP) 2020-11-04 EP disclosed
EP-3636446-A1 RECORDING MATERIAL AND COMPOUND Nippon Soda Co., Ltd. (JP) 2020-04-15 EP disclosed
US-20200086669-A1 RECORDING MATERIAL AND COMPOUND NIPPON SODA CO., LTD. (JP) 2020-03-19 US disclosed
EP-2484663-B1 PHENOLIC COMPOUND AND RECORDING MATERIAL NIPPON SODA CO (JP) 2019-07-17 EP disclosed
EP-2923851-B1 RECORDING MATERIAL PRODUCED USING NON-PHENOL COMPOUND NIPPON SODA CO (JP) 2019-05-01 EP disclosed
EP-2923851-A1 RECORDING MATERIAL PRODUCED USING NON-PHENOL COMPOUND Nippon Soda Co., Ltd. (JP) 2015-09-30 EP disclosed
US-8664157-B2 Recording material using phenol compound NIPPON SODA CO., LTD. (JP) 2014-03-04 US disclosed
US-8551911-B2 Recording material using phenolic compound NIPPON SODA CO., LTD. (JP) 2013-10-08 US disclosed
EP-2612847-A1 RECORDING MATERIAL USING PHENOL COMPOUND Nippon Soda Co., Ltd. (JP) 2013-07-10 EP disclosed
US-20130137570-A1 RECORDING MATERIAL USING PHENOL COMPOUND NIPPON SODA CO., LTD. (JP) 2013-05-30 US disclosed
US-8431513-B2 Phenolic compound and recording material NIPPON SODA CO., LTD. (JP) 2013-04-30 US disclosed
US-20120204763-A1 PHENOLIC COMPOUND AND RECORDING MATERIAL NIPPON SODA CO., LTD. 2012-08-16 US disclosed
EP-2484663-A1 PHENOLIC COMPOUND AND RECORDING MATERIAL Nippon Soda Co., Ltd. (JP) 2012-08-08 EP disclosed
EP-2484534-A1 RECORDING MATERIAL USING PHENOLIC COMPOUND Nippon Soda Co., Ltd. (JP) 2012-08-08 EP disclosed
US-20120186490-A1 RECORDING MATERIAL USING PHENOLIC COMPOUND NIPPON SODA CO., LTD. 2012-07-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11529819-B2 Recording material and compound H1-0, DOT1L, H1-4 ALDH1A1 1091/4885HSD17B10 2931/4885TP53 2871/4885
US-20120204763-A1 PHENOLIC COMPOUND AND RECORDING MATERIAL OR10J3, OR51E2, H1-4 ALDH1A1 1589/4885HSD17B10 3941/4885TP53 1497/4885
US-20200086669-A1 RECORDING MATERIAL AND COMPOUND H1-0, DOT1L, H1-4 ALDH1A1 1091/4885HSD17B10 2931/4885TP53 2871/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.