Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.51 |
| ▸ | ACHE | P22303 | 5/20 | 0.48 |
| ▸ | BCHE | P06276 | 2/20 | 0.47 |
| ▸ | SNCA | P37840 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CDC25C | P30307 | 1/20 | 0.41 |
| ▸ | GRK6 | P43250 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8744275 | 0.86 | MAPT (0.56) | MAPTNPSR1PTGS2ACHEBCHE | |
| SCHEMBL29559399 | 0.86 | MAPT (0.56) | MAPTNPSR1PTGS2ACHEBCHE | |
| SCHEMBL22897768 | 0.83 | MAPT (0.53) | MAPTNPSR1PTGS2ACHEBCHE | |
| SCHEMBL11622694 | 0.82 | MAPT (0.51) | MAPTNPSR1PTGS2ACHEBCHE | |
| SCHEMBL31016517 | 0.81 | MAPT (0.52) | MAPTNPSR1PTGS2ACHEBCHE | |
| SCHEMBL31361989 | 0.81 | MAPT (0.72) | MAPTNPSR1PTGS2ACHEBCHE | |
| SCHEMBL2038302 | 0.78 | MAPT (0.73) | MAPTNPSR1PTGS2ACHEBCHE | |
| SCHEMBL3878871 | 0.76 | MAPT (0.61) | MAPTNPSR1PTGS2ACHEBCHE | |
| SCHEMBL11353420 | 0.76 | MAPT (0.61) | MAPTNPSR1PTGS2ACHEBCHE | |
| SCHEMBL976044 | 0.76 | MAPT (0.61) | MAPTNPSR1PTGS2ACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0058332-B1 | PROCESS FOR THE MANUFACTURE OF ACRIDINE DYES | BAYER AG (DE) | 1985-01-02 | — | — | EP | disclosed |
| EP-0058332-A1 | Process for the manufacture of acridine dyes | BAYER AG (DE) | 1982-08-25 | — | — | EP | disclosed |