Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11223105 | 1.00 | MAPT (0.45) | MAPTIDO1TDO2PTPN1 | |
| SCHEMBL19231532 | 0.81 | MAPT (0.46) | MAPTIDO1TDO2PTPN1 | |
| SCHEMBL13479444 | 0.81 | MAPT (0.46) | MAPTIDO1TDO2PTPN1 | |
| SCHEMBL14279199 | 0.81 | MAPT (0.46) | MAPTIDO1TDO2PTPN1 | |
| SCHEMBL19168024 | 0.78 | MAPT (0.44) | MAPTIDO1TDO2 | |
| SCHEMBL14472687 | 0.76 | MAPT (0.61) | MAPTIDO1TDO2 | |
| SCHEMBL10033763 | 0.75 | MAPT (0.42) | MAPTIDO1TDO2 | |
| SCHEMBL11992942 | 0.75 | MAPT (0.42) | MAPTIDO1TDO2 | |
| SCHEMBL20349081 | 0.75 | MAPT (0.42) | MAPTIDO1TDO2 | |
| SCHEMBL23022360 | 0.73 | MAPT (0.55) | MAPTIDO1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0085158-B1 | PROCESS FOR THE PREPARATION OF CYCLOALKENON DERIVATIVES | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1985-06-19 | — | — | EP | disclosed |
| US-4465567-A | Process for the manufacture of 3-hydroxy-2-cycloalken-1-one derivatives | HOFFMANN-LA ROCHE INC. (US) | 1984-08-14 | — | — | US | disclosed |
| EP-0085158-A2 | Process for the preparation of cycloalkenon derivatives | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1983-08-10 | — | — | EP | disclosed |
| EP-0005748-B1 | PROCESS FOR THE PREPARATION OF CYCLOHEXENYL DERIVATIVES, AND INTERMEDIATES PRODUCED IN THE SYNTHESIS | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1982-12-29 | — | — | EP | disclosed |
| US-4283559-A | Process for the manufacture of cyclohexene derivatives | HOFFMANN-LA ROCHE INC. (US) | 1981-08-11 | — | — | US | disclosed |
| EP-0005748-A2 | Process for the preparation of cyclohexenyl derivatives, and intermediates produced in the synthesis | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1979-12-12 | — | — | EP | disclosed |