Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13265094 | 1.00 | MAPT (0.55) | MAPTIDO1TDO2 | |
| SCHEMBL13238908 | 0.82 | MAPT (0.58) | MAPTIDO1TDO2 | |
| SCHEMBL14472687 | 0.81 | MAPT (0.61) | MAPTIDO1TDO2 | |
| SCHEMBL14181277 | 0.80 | MAPT (0.57) | MAPTIDO1TDO2 | |
| SCHEMBL13400301 | 0.80 | MAPT (0.36) | MAPT | |
| SCHEMBL14495399 | 0.79 | MAPT (0.56) | MAPT | |
| SCHEMBL17506680 | 0.79 | MAPT (0.52) | MAPTIDO1TDO2 | |
| SCHEMBL14458091 | 0.79 | MAPT (0.52) | MAPTIDO1TDO2 | |
| SCHEMBL3126987 | 0.79 | MAPT (0.52) | MAPTIDO1TDO2 | |
| SCHEMBL19182461 | 0.79 | MAPT (0.52) | MAPTIDO1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210052537-A1 | COLITIS AMELIORATING AGENT | ASTA PHARMACEUTICALS, CO., LTD. (JP) | 2021-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210052537-A1 | COLITIS AMELIORATING AGENT | CRY1, FOXM1, SLC10A2 | MAPT 2620/4885IDO1 232/4885TDO2 1151/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.