SCHEMBL11028522

SCHEMBL11028522

CCCn1cc(C(=O)O)c(=O)c2cc(F)c(Cl)cc21

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.55
DRD3 P35462 1/20 0.55
HPGD P15428 4/20 0.51
KDM4E B2RXH2 4/20 0.51
HSD17B10 Q99714 3/20 0.51
LMNA P02545 2/20 0.51
BRD4 O60885 1/20 0.51
TSHR P16473 1/20 0.51
HTT P42858 1/20 0.51
CYP2J2 P51589 1/20 0.51
NPSR1 Q6W5P4 1/20 0.51
MEN1 O00255 4/20 0.50
KMT2A Q03164 4/20 0.50
NPC1 O15118 1/20 0.50
POLB P06746 1/20 0.48
TAAR1 Q96RJ0 1/20 0.48
CYP1A2 P05177 1/20 0.47
CYP2D6 P10635 1/20 0.47
APEX1 P27695 1/20 0.47
TDP1 Q9NUW8 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10531029 0.92 ALDH1A1 (0.52) ALDH1A1DRD3HPGDKDM4EHSD17B10
SCHEMBL10658569 0.90 ALDH1A1 (0.63) ALDH1A1DRD3HPGDKDM4EHSD17B10
SCHEMBL3809668 0.90 DRD3 (0.63) ALDH1A1DRD3HPGDKDM4EHSD17B10
SCHEMBL29548224 0.90 DRD3 (0.63) ALDH1A1DRD3HPGDKDM4EHSD17B10
SCHEMBL15282020 0.90 ALDH1A1 (0.59) ALDH1A1DRD3HPGDKDM4EHSD17B10
SCHEMBL6214038 0.89 ALDH1A1 (0.53) ALDH1A1DRD3HPGDKDM4EHSD17B10
SCHEMBL541723 0.89 DRD3 (0.61) ALDH1A1DRD3HPGDKDM4EHSD17B10
SCHEMBL541724 0.89 DRD3 (0.61) ALDH1A1DRD3HPGDKDM4EHSD17B10
Hydrochloric Acid SCHEMBL28333431 0.89 DRD3 (0.61) ALDH1A1DRD3HPGDKDM4EHSD17B10
Fluoride SCHEMBL6764129 0.88 DRD3 (0.60) ALDH1A1DRD3HPGDKDM4EHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4448962-A BACTERICIDES KYORIN SEIYAKU KABUSHIKI KAISHA 1984-05-15 US disclosed