Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.58 |
| ▸ | TACR1 | P25103 | 2/20 | 0.53 |
| ▸ | PLAU | P00749 | 1/20 | 0.52 |
| ▸ | PLAT | P00750 | 1/20 | 0.52 |
| ▸ | CTSL | P07711 | 2/20 | 0.52 |
| ▸ | CTSK | P43235 | 2/20 | 0.52 |
| ▸ | CTSB | P07858 | 1/20 | 0.52 |
| ▸ | CTSS | P25774 | 1/20 | 0.52 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.51 |
| ▸ | MMP8 | P22894 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11126448 | 0.90 | BCL2 (0.59) | HDAC8CTSLCTSKCTSBCTSS | |
| SCHEMBL10824232 | 0.86 | MME (0.50) | F2HDAC8CTSBMMP9MMP8 | |
| SCHEMBL14376753 | 0.84 | F2 (0.63) | F2PLAUPLAT | |
| SCHEMBL11028529 | 0.82 | HDAC8 (0.51) | F2HDAC8TACR1CTSLCTSK | |
| SCHEMBL11034687 | 0.81 | MME (0.51) | HDAC8 | |
| SCHEMBL282500 | 0.81 | BCL2 (0.52) | F2HDAC8PLAUPLAT | |
| SCHEMBL11126449 | 0.80 | BCL2 (0.49) | HDAC8CTSKCTSS | |
| SCHEMBL10784747 | 0.80 | CAPN1 (0.64) | HDAC8CTSLCTSKCTSBCTSS | |
| SCHEMBL9483283 | 0.79 | PPARG (0.67) | HDAC8CTSLCTSKCTSBCTSS | |
| SCHEMBL9483288 | 0.79 | PPARG (0.67) | HDAC8CTSLCTSKCTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0061172-B1 | PHOSPHORUS-CONTAINING OLIGOPEPTIDES, PROCESSES FOR PREPARATION THEREOF AND A PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1985-06-19 | — | — | EP | disclosed |
| EP-0061172-A1 | Phosphorus-containing oligopeptides, processes for preparation thereof and a pharmaceutical composition containing the same | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1982-09-29 | — | — | EP | disclosed |