Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 2/20 | 0.50 |
| ▸ | ACE | P12821 | 2/20 | 0.50 |
| ▸ | CPA1 | P15085 | 2/20 | 0.50 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.43 |
| ▸ | IL1RN | P18510 | 1/20 | 0.43 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.43 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.43 |
| ▸ | EED | O75530 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11028528 | 0.86 | F2 (0.58) | MMP9MMP8CTSBF2HDAC8 | |
| SCHEMBL11126448 | 0.82 | BCL2 (0.59) | CTSBHDAC8 | |
| SCHEMBL11034687 | 0.80 | MME (0.51) | MMEACECPA1ACE2HDAC8 | |
| SCHEMBL12894592 | 0.77 | LMNA (0.58) | LMNAL3MBTL1PPARG | |
| SCHEMBL282500 | 0.76 | BCL2 (0.52) | F2PPARGHDAC8 | |
| SCHEMBL10728394 | 0.74 | MME (0.60) | MMEACECPA1ACE2MMP9 | |
| SCHEMBL11126449 | 0.73 | BCL2 (0.49) | HDAC8 | |
| SCHEMBL10726106 | 0.73 | MME (0.56) | MMEACECPA1ACE2MMP9 | |
| SCHEMBL10723826 | 0.73 | MME (0.58) | MMEACECPA1ACE2MMP9 | |
| SCHEMBL10726089 | 0.73 | MME (0.58) | MMEACECPA1ACE2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-61036287-A | — | — | None | — | — | JP | disclosed |
| JP-S6136287-A | PHOSPHORUS-CONTAINING PEPTIDE DERIVATIVE | KYOWA HAKKO KOGYO CO LTD | 1986-02-20 | — | — | JP | disclosed |