Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 15/20 | 0.69 |
| ▸ | AR | P10275 | 15/20 | 0.69 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.69 |
| ▸ | LMNA | P02545 | 4/20 | 0.69 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.69 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.69 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.69 |
| ▸ | HTR2B | P41595 | 2/20 | 0.69 |
| ▸ | HTR2A | P28223 | 1/20 | 0.69 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | NR3C2 | P08235 | 4/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11026949 | 0.91 | PGR (0.71) | PGRARNR3C1LMNAABCB11 | |
| SCHEMBL14668731 | 0.87 | PGR (0.79) | PGRARNR3C1LMNAABCB11 | |
| SCHEMBL14256379 | 0.87 | PGR (0.79) | PGRARNR3C1LMNAABCB11 | |
| SCHEMBL18220876 | 0.87 | PGR (0.79) | PGRARNR3C1LMNAABCB11 | |
| SCHEMBL8025172 | 0.87 | PGR (0.79) | PGRARNR3C1LMNAABCB11 | |
| SCHEMBL16329005 | 0.87 | PGR (0.79) | PGRARNR3C1LMNAABCB11 | |
| SCHEMBL11028359 | 0.85 | PGR (0.51) | PGRARNR3C1LMNAABCB11 | |
| SCHEMBL11029288 | 0.82 | PGR (0.71) | PGRARNR3C1LMNAABCB11 | |
| Drospirenone SCHEMBL3073676 | 0.82 | PGR (0.93) | PGRARNR3C1LMNAABCB11 | |
| SCHEMBL22171518 | 0.82 | PGR (0.76) | PGRARNR3C1LMNAABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0061418-B1 | 7-ALPHA-ALKOXYCARBONYL-15-BETA-16-BETA-METHYLENE-4 ANDROSTENE, PROCESS FOR THEIR PREPARATION AND THEIR UTILIZATION AS PHARMACEUTICAL PREPARATIONS | SCHERING AKTIENGESELLSCHAFT (DE) | 1985-08-21 | — | — | EP | claimed |
| US-4450107-A | 7α-Alkoxycarbonyl-15β,16β-methylene-4-androstenes, process for the preparation thereof, and use thereof as medicinal agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1984-05-22 | — | — | US | claimed |
| EP-0061418-A1 | 7-Alpha-alkoxycarbonyl-15-beta-16-beta-methylene-4 androstene, process for their preparation and their utilization as pharmaceutical preparations | SCHERING AKTIENGESELLSCHAFT (DE) | 1982-09-29 | — | — | EP | claimed |
| EP-0061418-B1 | 7-ALPHA-ALKOXYCARBONYL-15-BETA-16-BETA-METHYLENE-4 ANDROSTENE, PROCESS FOR THEIR PREPARATION AND THEIR UTILIZATION AS PHARMACEUTICAL PREPARATIONS | SCHERING AKTIENGESELLSCHAFT (DE) | 1985-08-21 | — | — | EP | disclosed |
| US-4450107-A | 7α-Alkoxycarbonyl-15β,16β-methylene-4-androstenes, process for the preparation thereof, and use thereof as medicinal agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1984-05-22 | — | — | US | disclosed |