Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5598801 | 0.91 | ALPI (0.38) | CYP1A2SLC7A5 | |
| SCHEMBL3194235 | 0.90 | — | — | |
| SCHEMBL5050431 | 0.90 | — | — | |
| SCHEMBL29271692 | 0.89 | ALOX15 (0.32) | — | |
| SCHEMBL259086 | 0.89 | GSR (0.34) | — | |
| SCHEMBL3948451 | 0.89 | GSR (0.37) | — | |
| SCHEMBL5155910 | 0.88 | GSR (0.33) | — | |
| SCHEMBL7586770 | 0.88 | CYP3A4 (0.30) | CYP3A4SLC7A5 | |
| SCHEMBL27693420 | 0.85 | — | — | |
| SCHEMBL15023743 | 0.84 | GSR (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0079464-B1 | THIAZOLIDINE-4-CARBOXYLIC-ACID DERIVATIVE, PROCESS FOR ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT | YASON S.r.l (IT) | 1985-08-14 | — | — | EP | disclosed |
| US-4447419-A | ANGIOTENSIN INHIBITOR, HYPOTENSIVE AGENT, BRONCHODILATOR, AND TREATMENT OF LIVER DISORDERS | AUSONIA FARMACEUTICI S.R.L. (IT) | 1984-05-08 | — | — | US | disclosed |
| EP-0079464-A1 | Thiazolidine-4-carboxylic-acid derivative, process for its preparation and pharmaceutical compositions containing it | YASON S.r.l (IT) | 1983-05-25 | — | — | EP | disclosed |