Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17431102 | 0.91 | CNR2 (0.49) | CNR2MAPTNR1H2NR1H3GAA | |
| SCHEMBL17663673 | 0.91 | CNR2 (0.49) | CNR2MAPTNR1H2NR1H3GAA | |
| SCHEMBL14564613 | 0.91 | CNR2 (0.49) | CNR2MAPTNR1H2NR1H3GAA | |
| SCHEMBL6565246 | 0.89 | EGFR (0.47) | CNR2NR1H2NR1H3EGFRERBB2 | |
| SCHEMBL107013 | 0.85 | CNR2 (0.49) | CNR2MAPTNR1H2NR1H3GAA | |
| SCHEMBL17431097 | 0.84 | CYP2C19 (0.50) | CNR2MAPTNR1H2NR1H3GAA | |
| SCHEMBL21391890 | 0.84 | NPC1 (0.49) | CNR2MAPTNR1H2NR1H3GAA | |
| Hydrochloric Acid SCHEMBL2141325 | 0.83 | CNR2 (0.48) | CNR2MAPTNR1H2NR1H3GAA | |
| SCHEMBL18074044 | 0.83 | CNR2 (0.48) | CNR2MAPTNR1H2NR1H3GAA | |
| SCHEMBL17663681 | 0.83 | EGFR (0.47) | CNR2MAPTNR1H2NR1H3GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4490559-A | SYNTHESIS GAS AND A GROUP VII COMPOUND CATALYST | SHELL OIL COMPANY (US) | 1984-12-25 | — | — | US | disclosed |