Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 10/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.46 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.46 |
| ▸ | CNR2 | P34972 | 3/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28598991 | 0.92 | CNR2 (0.54) | EGFRERBB2KCNH2CNR2 | |
| SCHEMBL11029155 | 0.89 | CNR2 (0.44) | EGFRERBB2KCNH2NR1H2NR1H3 | |
| SCHEMBL7153351 | 0.89 | EGFR (0.50) | EGFRERBB2NR1H2NR1H3CNR2 | |
| SCHEMBL7790003 | 0.86 | CNR2 (0.46) | EGFRERBB2KCNH2CNR2 | |
| SCHEMBL17663681 | 0.84 | EGFR (0.47) | EGFRERBB2NR1H2NR1H3CNR2 | |
| SCHEMBL2014159 | 0.84 | EGFR (0.47) | EGFRERBB2NR1H2NR1H3CNR2 | |
| SCHEMBL768272 | 0.84 | EGFR (0.47) | EGFRERBB2NR1H2NR1H3CNR2 | |
| SCHEMBL3347146 | 0.82 | CNR2 (0.47) | EGFRERBB2KCNH2NR1H2NR1H3 | |
| SCHEMBL3054212 | 0.82 | EGFR (0.46) | EGFRERBB2NR1H2NR1H3CNR2 | |
| SCHEMBL1459455 | 0.81 | EGFR (0.44) | EGFRERBB2NR1H2NR1H3CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110066383-A | A kind of aqueous epoxy curing agent of ionic and its preparation method and application | 万华化学集团股份有限公司 | 2019-07-30 | — | — | CN | disclosed |
| US-10040949-B2 | Thermosetting powder coating material and coated article | FUJI XEROX CO., LTD. (JP) | 2018-08-07 | — | — | US | disclosed |
| CN-108285526-A | A kind of modified alicyclic ring amine hardener and preparation method thereof | 万华化学集团股份有限公司 | 2018-07-17 | — | — | CN | disclosed |
| US-20160280930-A1 | THERMOSETTING POWDER COATING MATERIAL AND COATED ARTICLE | FUJIFILM BUSINESS INNOVATION CORP. (JP) | 2016-09-29 | — | — | US | disclosed |
| EP-0835891-B1 | Water-dispersible blocked isocyanate composition, and water-base paint composition and water base adhesive composition using the same | NIPPON POLYURETHANE KOGYO KK (JP) | 2004-03-31 | — | — | EP | disclosed |
| US-6080812-A | TRIMERIZING A DIISOCYANATE-DIOL-DIISOCYANATE CONDENSATION PRODUCT TO FORM ISOCYANURATE MACROMOLECULAR MONOMER, REACTING WITH HYDROPHILIC SURFACTANT TO FORM A URETHANE/ISOCYANURATE COPOLYMER, THEN BLOCKING REMAINING ISOCYANATE GROUPS | NIPPON POLYURETHANE INDUSTRY C. LTD. (JP) | 2000-06-27 | — | — | US | disclosed |
| US-5998539-A | ISOCYANATE BLOCKED WITH AN ALCOHOL | NIPPON POLYURETHANE INDUSTRY CO., LTD. (JP) | 1999-12-07 | — | — | US | disclosed |
| EP-0835891-A1 | Water-dispersible blocked isocyanate composition, and water-base paint composition and water base adhesive composition using the same | Nippon Polyurethane Industry Co. Ltd. (JP) | 1998-04-15 | — | — | EP | disclosed |