Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGALS8 | O00214 | 2/20 | 0.45 |
| ▸ | GBA1 | P04062 | 8/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MGAM | O43451 | 4/20 | 0.41 |
| ▸ | SI | P14410 | 4/20 | 0.41 |
| ▸ | OGA | O60502 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11029229 | 1.00 | LGALS8 (0.45) | LGALS8GBA1MAPK1MGAMSI | |
| SCHEMBL9231772 | 0.83 | GBA1 (0.54) | LGALS8GBA1MAPK1 | |
| SCHEMBL9231776 | 0.83 | GBA1 (0.54) | LGALS8GBA1MAPK1 | |
| SCHEMBL10880031 | 0.81 | MAPK1 (0.56) | LGALS8GBA1MAPK1 | |
| SCHEMBL10880043 | 0.81 | MAPK1 (0.56) | LGALS8GBA1MAPK1 | |
| SCHEMBL10882040 | 0.77 | MAPK1 (0.62) | LGALS8GBA1MAPK1 | |
| SCHEMBL10882036 | 0.77 | MAPK1 (0.62) | LGALS8GBA1MAPK1 | |
| SCHEMBL21105395 | 0.75 | MGAM (0.47) | LGALS8GBA1MGAMSI | |
| SCHEMBL31001202 | 0.75 | GBA1 (0.49) | GBA1MAPK1OGA | |
| SCHEMBL21059535 | 0.75 | GBA1 (0.49) | GBA1MAPK1OGA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0056458-B1 | NITROSOUREA DERIVATIVES, A PROCESS FOR PREPARING SAME AND THERAPEUTIC COMPOSITIONS | Tanabe Seiyaku Co., Ltd. (JP) | 1985-05-02 | — | — | EP | disclosed |
| EP-0056458-A1 | Nitrosourea derivatives, a process for preparing same and therapeutic compositions | Tanabe Seiyaku Co., Ltd. (JP) | 1982-07-28 | — | — | EP | disclosed |