LGALS8 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL701054	0.56	8/20
SCHEMBL661256	0.55	8/20
SCHEMBL661257	0.55	8/20
SCHEMBL264210	0.50	8/20
SCHEMBL176296	0.71	7/20
SCHEMBL564651	0.44	7/20
SCHEMBL897124	0.46	6/20
SCHEMBL229813	0.56	5/20
SCHEMBL1097983	0.56	5/20
SCHEMBL979254	0.39	4/20
SCHEMBL280278	0.36	4/20
SCHEMBL154476	0.32	4/20
SCHEMBL423526	0.32	4/20
SCHEMBL411273	0.77	3/20
SCHEMBL411274	0.77	3/20
SCHEMBL411624	0.77	3/20
SCHEMBL411625	0.77	3/20
SCHEMBL736151	0.77	3/20
SCHEMBL416471	0.72	3/20
SCHEMBL754690	0.67	3/20

Clinical trials — most relevant to LGALS8 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
A Phase 2b Study of GCS-100 in Patients With Chronic Kidney Disease Caused by Diabetes	PHASE2	UNKNOWN
A Phase 2 Extension of Study GCS-100-CS-4003	PHASE2	WITHDRAWN
A Phase 2a Study of Weekly Doses of GCS-100 in Patients With Chronic Kidney Disease	PHASE2	COMPLETED
Vitamin D Deficiency Treatment Outcomes After Non-ST-Segment Elevation Myocardial Infarction	PHASE2	UNKNOWN
A Phase 2 Extension Study of Study GCS-100-CS-4002	PHASE2	COMPLETED
Study on Mannan Binding Lectin (MBL) Substitution in MBL-Deficient Children With Chemotherapy-Induced Neutropenia	PHASE2	COMPLETED
Effect of Modified Citrus Pectin on PSA Kinetics in Biochemical Relapsed PC With Serial Increases in PSA	PHASE2	COMPLETED
GR-MD-02 Plus Pembrolizumab in Melanoma, Non-small Cell Lung Cancer, and Squamous Cell Head and Neck Cancer Patients	PHASE1	COMPLETED
The Diagnostic Value of Serum Oncostatin M and Galactin 3 as Biomarkers in Diagnosis of Ulcerative Colitis Disease	nan	NOT_YET_RECRUITING
Effect of Low-Glycemic Index Mediterranean Diet on AGEs	nan	COMPLETED
A Serum Galectin-3 Levels in Placenta Accreta Spectrum Pregnancies	nan	COMPLETED
A Wearable Device and AI-Supported Diet and Exercise Intervention	nan	RECRUITING
Galectin and Respiratory Weaning	nan	UNKNOWN
Galectin-3 for Thromboembolic Formation in Patients With Atrial Fibrillation CHA₂DS₂-VASc Scoring	nan	UNKNOWN
Urinary G3BP as a Novel Biomarker in Lupus Nephritis	nan	NOT_YET_RECRUITING
The Role of Galectins in the Non-invasive Diagnosis of Endometriosis	nan	UNKNOWN
Galectin-3 Binding Protein in Cardiovascular Disease and Chronic Heart Failure	nan	COMPLETED
Galectin-3 as a Biomarker in Patients With Chagas Disease	nan	COMPLETED
Galectin-3 in Septic and Non-septic Acute Kidney Injury	nan	UNKNOWN
Galectin 3 Dosage in Diagnosis of Nodular and Multinodular Goiter	nan	COMPLETED
Evaluation of Serum Galectin-9 Level in Systemic Lupus Erythematosus Patients and it's Association With Disease Activity and Organ Damage	nan	UNKNOWN
Testicular Proteins for Sperm Retrieval Prediction Protein1, Testis-Expressed Gene 101, and Lectin Galactoside-binding Protein in Predicting Surgical Sperm Retrieval in Men With Non-Obstructive Azoospermia	nan	UNKNOWN
Early Gestational Diabetes Screening in the Gravid Obese Woman	nan	COMPLETED
Galectin-3 in Patients With Endometriosis	nan	UNKNOWN
Glycoprotein and Glycan in Tissue and Blood Samples of Patients With Stage IB-IVA Cervical Cancer Undergoing Surgery to Remove Pelvic and Abdominal Lymph Nodes	nan	COMPLETED
Minimally Invasive Kidney Transplantation	nan	UNKNOWN
Biomarkers for Risk Stratification After STEMI	nan	UNKNOWN
Evaluation of Galectin-3 in Serum and Saliva of Pemphigus Patients	nan	UNKNOWN
Biomarkers of Lichen Sclerosus	nan	UNKNOWN
Blood Collection From Heart Failure Patients to Evaluate for Galectin-3 Measurement Differences Using Various Collection Tubes	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a LGALS8 binder may also engage these)

Protein	Name	Similarity
Q62665	—	1.000	Q62665 →
Q9JL15	—	0.997	Q9JL15 →
O54891	—	0.982	O54891 →
Q9UHV8	—	0.980	Q9UHV8 →
Q05315	—	0.978	Q05315 →
Q8TCE9	—	0.974	Q8TCE9 →
Q29058	—	0.972	Q29058 →
P07583	—	0.972	P07583 →
P11762	—	0.971	P11762 →
Q9Z144	—	0.970	Q9Z144 →
P97840	—	0.969	P97840 →
P47967	—	0.969	P47967 →
O08573	—	0.969	O08573 →
Q5R7M1	—	0.969	Q5R7M1 →
O44126	—	0.968	O44126 →
A8MUM7	—	0.968	A8MUM7 →
C0HJR3	—	0.968	C0HJR3 →
LGALS4	Galectin-4	0.967	landscape →
Q3MHZ8	—	0.966	Q3MHZ8 →
P36573	—	0.966	P36573 →
P38552	—	0.965	P38552 →
Q6DKI2	—	0.965	Q6DKI2 →
P16045	—	0.964	P16045 →
Q6DGJ1	—	0.963	Q6DGJ1 →
Q9CQW5	—	0.963	Q9CQW5 →
P97590	—	0.963	P97590 →
Q49I35	—	0.963	Q49I35 →
Q3B8N2	—	0.961	Q3B8N2 →
C0HJQ1	—	0.961	C0HJQ1 →
Q09581	—	0.961	Q09581 →