SCHEMBL1102930

SCHEMBL1102930

c1ccc(-c2ccc(-c3c4ccccc4c(-c4ccc(-c5ccccc5)c5ccccc45)c4ncccc34)c3ccccc23)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CKS1B P61024 8/20 0.49
SKP2 Q13309 8/20 0.49
GLO1 Q04760 5/20 0.49
COMT P21964 1/20 0.44
TOP1 P11387 3/20 0.44
HSP90AA1 P07900 2/20 0.38
NPC1 O15118 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
KDM4E B2RXH2 2/20 0.38
IKBKB O14920 1/20 0.38
CHUK O15111 1/20 0.38
DAPK3 O43293 1/20 0.38
JAK2 O60674 1/20 0.38
PRKD3 O94806 1/20 0.38
MAP4K4 O95819 1/20 0.38
PAK4 O96013 1/20 0.38
CSF1R P07333 1/20 0.38
RET P07949 1/20 0.38
IGF1R P08069 1/20 0.38
FGFR1 P11362 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1102984 0.95 CKS1B (0.48) CKS1BSKP2GLO1COMTTOP1
SCHEMBL1103101 0.91 CKS1B (0.43) CKS1BSKP2GLO1COMTTOP1
SCHEMBL1103187 0.91 TNF (0.46) CKS1BSKP2GLO1COMTTOP1
SCHEMBL1102848 0.89 TOP1 (0.44) CKS1BSKP2GLO1COMTTOP1
SCHEMBL1103061 0.88 CKS1B (0.48) CKS1BSKP2GLO1COMTTOP1
SCHEMBL1102974 0.86 TOP1 (0.41) CKS1BSKP2GLO1COMTTOP1
SCHEMBL1103088 0.84 KDM4E (0.40) CKS1BSKP2GLO1TOP1HSP90AA1
SCHEMBL1103197 0.84 TNF (0.43) CKS1BSKP2GLO1TOP1HSP90AA1
SCHEMBL1103042 0.84 TOP1 (0.42) CKS1BSKP2GLO1COMTTOP1
SCHEMBL1103131 0.84 TOP1 (0.41) CKS1BSKP2GLO1COMTTOP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8153279-B2 Organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2012-04-10 US disclosed
US-8153279-B2 Organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2012-04-10 US disclosed
US-20100033083-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-02-11 US disclosed
US-20100033083-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-02-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100033083-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same ORMDL3, OCIAD2, OCIAD1 CKS1B 3839/4885SKP2 1787/4885GLO1 3498/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.