Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 6/20 | 0.41 |
| ▸ | CKS1B | P61024 | 4/20 | 0.40 |
| ▸ | SKP2 | Q13309 | 4/20 | 0.40 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.40 |
| ▸ | COMT | P21964 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1102848 | 0.97 | TOP1 (0.44) | TOP1CKS1BSKP2GLO1COMT | |
| SCHEMBL1103002 | 0.95 | TOP1 (0.41) | TOP1CKS1BSKP2GLO1COMT | |
| SCHEMBL1103042 | 0.92 | TOP1 (0.42) | TOP1CKS1BSKP2GLO1COMT | |
| SCHEMBL1103202 | 0.91 | TNF (0.41) | TOP1CKS1BSKP2GLO1ENPP1 | |
| SCHEMBL1103197 | 0.88 | TNF (0.43) | TOP1CKS1BSKP2GLO1ENPP1 | |
| SCHEMBL1102930 | 0.86 | CKS1B (0.49) | TOP1CKS1BSKP2GLO1COMT | |
| SCHEMBL1103143 | 0.86 | TOP1 (0.40) | TOP1MMP2DHODHHSP90AA1L3MBTL1 | |
| SCHEMBL1103135 | 0.84 | TOP1 (0.41) | TOP1MMP2DHODHHSP90AA1L3MBTL1 | |
| SCHEMBL1102949 | 0.82 | L3MBTL1 (0.41) | TOP1CKS1BSKP2GLO1MMP2 | |
| SCHEMBL1102990 | 0.82 | L3MBTL1 (0.41) | TOP1CKS1BSKP2GLO1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8153279-B2 | Organic electroluminescent compounds and organic electroluminescent device using the same | GRACEL DISPLAY INC. (KR) | 2012-04-10 | — | — | US | disclosed |
| US-8153279-B2 | Organic electroluminescent compounds and organic electroluminescent device using the same | GRACEL DISPLAY INC. (KR) | 2012-04-10 | — | — | US | disclosed |
| US-20100033083-A1 | Novel organic electroluminescent compounds and organic electroluminescent device using the same | GRACEL DISPLAY INC. (KR) | 2010-02-11 | — | — | US | disclosed |
| US-20100033083-A1 | Novel organic electroluminescent compounds and organic electroluminescent device using the same | GRACEL DISPLAY INC. (KR) | 2010-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100033083-A1 | Novel organic electroluminescent compounds and organic electroluminescent device using the same | ORMDL3, OCIAD2, OCIAD1 | TOP1 4307/4885CKS1B 3839/4885SKP2 1787/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.