SCHEMBL11029451

SCHEMBL11029451

C/C=C/C=C/CCC(=O)C(C)(C)C

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 9/20 0.44
CNR1 P21554 7/20 0.44
TRPA1 O75762 1/20 0.44
TRPV1 Q8NER1 1/20 0.44
SOAT1 P35610 1/20 0.41
PPARG P37231 2/20 0.39
PPARD Q03181 2/20 0.39
PPARA Q07869 2/20 0.39
FASN P49327 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11029452 1.00 CNR2 (0.44) CNR2CNR1TRPA1TRPV1SOAT1
SCHEMBL15821693 0.83 ALDH1A1 (0.33) CNR2CNR1TRPA1TRPV1PPARG
SCHEMBL15821694 0.83 ALDH1A1 (0.33) CNR2CNR1TRPA1TRPV1PPARG
SCHEMBL11027832 0.79 LSS (0.35)
SCHEMBL11027834 0.79 LSS (0.35)
SCHEMBL10300851 0.76 CNR2 (0.39) CNR2CNR1TRPA1TRPV1SOAT1
SCHEMBL6125309 0.76 CNR2 (0.39) CNR2CNR1TRPA1TRPV1SOAT1
SCHEMBL1873469 0.76 FASN (0.48) CNR2CNR1TRPA1TRPV1SOAT1
SCHEMBL22092407 0.76 FASN (0.48) CNR2CNR1TRPA1TRPV1SOAT1
SCHEMBL8670164 0.76 SOAT1 (0.49) CNR2CNR1TRPA1TRPV1SOAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0045861-B1 UNSATURATED COMPOUNDS, PROCESS FOR THEIR PREPARATION, THEIR USE AS PERFUMES AND THE PERFUMED COMPOSITIONS CONTAINING THEM L. GIVAUDAN & CIE Société Anonyme (CH) 1984-10-03 EP claimed
US-4426321-A Odorant alkadienyl ketones, alcohols and oximes GIVAUDAN CORPORATION (US) 1984-01-17 US claimed
EP-0045861-A2 Unsaturated compounds, process for their preparation, their use as perfumes and the perfumed compositions containing them L. GIVAUDAN & CIE Société Anonyme (CH) 1982-02-17 EP claimed
EP-0045861-B1 UNSATURATED COMPOUNDS, PROCESS FOR THEIR PREPARATION, THEIR USE AS PERFUMES AND THE PERFUMED COMPOSITIONS CONTAINING THEM L. GIVAUDAN & CIE Société Anonyme (CH) 1984-10-03 EP disclosed
US-4426321-A Odorant alkadienyl ketones, alcohols and oximes GIVAUDAN CORPORATION (US) 1984-01-17 US disclosed
EP-0045861-A2 Unsaturated compounds, process for their preparation, their use as perfumes and the perfumed compositions containing them L. GIVAUDAN & CIE Société Anonyme (CH) 1982-02-17 EP disclosed