Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6451911 | 1.00 | DRD2 (0.40) | DRD2MEN1NPC1CYP1A2GAA | |
| SCHEMBL6451908 | 1.00 | DRD2 (0.40) | DRD2MEN1NPC1CYP1A2GAA | |
| SCHEMBL6453962 | 0.95 | CFTR (0.39) | DRD2 | |
| SCHEMBL6453957 | 0.95 | CFTR (0.39) | DRD2 | |
| SCHEMBL6456109 | 0.95 | CFTR (0.39) | DRD2 | |
| SCHEMBL11030592 | 0.95 | CFTR (0.39) | DRD2 | |
| SCHEMBL6458242 | 0.94 | CFTR (0.41) | DRD2MEN1GAAMAPTKMT2A | |
| SCHEMBL6458244 | 0.94 | CFTR (0.41) | DRD2MEN1GAAMAPTKMT2A | |
| SCHEMBL6458082 | 0.94 | CFTR (0.41) | DRD2MEN1GAAMAPTKMT2A | |
| SCHEMBL6458084 | 0.94 | CFTR (0.41) | DRD2MEN1GAAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4432885-A | Decalins | HOFFMANN-LA ROCHE INC. (US) | 1984-02-21 | — | — | US | disclosed |