SCHEMBL11030152

SCHEMBL11030152

CCOCC(O)C(Cl)(Cl)Cl

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.35
LMNA P02545 1/20 0.32
HSD17B10 Q99714 1/20 0.31
TSHR P16473 1/20 0.31
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8645129 0.77 TSHR (0.50) HSD17B10TSHRALDH1A1
SCHEMBL309463 0.75 CETP (0.40) HSD17B10TSHRALDH1A1
SCHEMBL311426 0.75 CETP (0.40) HSD17B10TSHRALDH1A1
SCHEMBL309462 0.75 CETP (0.40) HSD17B10TSHRALDH1A1
SCHEMBL2997521 0.73 TSHR (0.32) HSD17B10TSHR
SCHEMBL31685204 0.73 CETP (0.39) HSD17B10
SCHEMBL1772943 0.70
SCHEMBL489357 0.69
SCHEMBL698450 0.69 KDM4E (0.46) HSD17B10TSHRALDH1A1
SCHEMBL28007845 0.69 ALDH1A1 (0.45) HSD17B10TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4482651-A Process for the preparation of haloalkoxymethylmelamine adduct dispersions and polyurethane compositions prepared therefrom BASF WYANDOTTE CORPORATION (US) 1984-11-13 US disclosed
EP-0056582-A1 Process for the preparation of polyisocyanurate dispersions modified with halogenated alcohols and compositions prepared therefrom BASF WYANDOTTE CORPORATION (US) 1982-07-28 EP disclosed
US-4334052-A Rigid, non-cellular polyurethane modified with reaction product of an isocyanate and an alcohol BASF WYANDOTTE CORPORATION (US) 1982-06-08 US disclosed
US-4334032-A Foamed polymers containing low molecular weight urethane modifier compound BASF WYANDOTTE CORPORATION (US) 1982-06-08 US disclosed
US-4326043-A FIREPROOFING BASF WYANDOTTE CORPORATION (US) 1982-04-20 US disclosed