Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11029825 | 0.80 | ALDH1A1 (0.57) | POLBSMN1; SMN2HPGDGAAALDH1A1 | |
| SCHEMBL2639127 | 0.78 | SMN1; SMN2 (0.69) | POLBSMN1; SMN2HPGDALOX15TDP1 | |
| SCHEMBL13774772 | 0.77 | ALDH1A1 (0.67) | POLBSMN1; SMN2HPGDALOX15TDP1 | |
| SCHEMBL11032051 | 0.77 | SMN1; SMN2 (0.74) | SMN1; SMN2HPGDGAAALDH1A1KMT2A | |
| SCHEMBL5079211 | 0.77 | POLB (0.61) | POLBSMN1; SMN2HPGDALOX15TDP1 | |
| SCHEMBL5079207 | 0.77 | POLB (0.61) | POLBSMN1; SMN2HPGDALOX15TDP1 | |
| SCHEMBL7596100 | 0.76 | MME (0.56) | HPGDALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL9369229 | 0.75 | SMN1; SMN2 (0.72) | POLBSMN1; SMN2HPGDALOX15TDP1 | |
| SCHEMBL31136182 | 0.75 | SMN1; SMN2 (0.59) | POLBSMN1; SMN2HPGDALOX15TDP1 | |
| Benzene SCHEMBL10806303 | 0.74 | SMN1; SMN2 (0.73) | POLBSMN1; SMN2HPGDALOX15TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0159254-A1 | Derivatives of omega-mercaptopropanamide and their salts, their preparation, their use as medicines and compositions containing them | ROUSSEL-UCLAF (FR) | 1985-10-23 | — | — | EP | claimed |
| EP-0159254-A1 | Derivatives of omega-mercaptopropanamide and their salts, their preparation, their use as medicines and compositions containing them | ROUSSEL-UCLAF (FR) | 1985-10-23 | — | — | EP | disclosed |