Sugi Predict

Sugi Predict / Compounds / SCHEMBL11030583

SCHEMBL11030583

SCHEMBL11030583

c1ccc2nc(Oc3cnc4ccccc4n3)cnc2c1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HTT P42858 10/20 0.77
▸ ALDH1A1 P00352 6/20 0.77
▸ MEN1 O00255 4/20 0.67
▸ KMT2A Q03164 4/20 0.67
▸ RAB9A P51151 3/20 0.67
▸ NPC1 O15118 2/20 0.67
▸ L3MBTL1 Q9Y468 2/20 0.67
▸ HPGD P15428 2/20 0.67
▸ ATM Q13315 1/20 0.67
▸ NPSR1 Q6W5P4 1/20 0.67
▸ RXFP1 Q9HBX9 1/20 0.67
▸ CYP1A2 P05177 2/20 0.61
▸ CYP2C19 P33261 2/20 0.61
▸ CYP2C9 P11712 1/20 0.61
▸ LMNA P02545 2/20 0.57
▸ PDE10A Q9Y233 1/20 0.50
▸ SMN1; SMN2 Q16637 2/20 0.49
▸ MAPT P10636 2/20 0.49
▸ GLA P06280 1/20 0.49
▸ CYP3A4 P08684 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formaldehyde SCHEMBL28251520 0.94 HTT (0.69) HTTALDH1A1MEN1KMT2ARAB9A
SCHEMBL8880504 0.87 HTT (1.00) HTTALDH1A1MEN1KMT2ARAB9A
SCHEMBL28236582 0.84 HTT (0.57) HTTALDH1A1MEN1KMT2ARAB9A
SCHEMBL28251521 0.84 HTT (0.57) HTTALDH1A1MEN1KMT2ARAB9A
SCHEMBL8712114 0.82 HTT (0.68) HTTALDH1A1MEN1KMT2ARAB9A
SCHEMBL9815623 0.82 HTT (0.66) HTTALDH1A1MEN1KMT2ARAB9A
SCHEMBL6002434 0.82 HTT (0.60) HTTALDH1A1MEN1KMT2ARAB9A
SCHEMBL9282533 0.82 HTT (0.60) HTTALDH1A1MEN1KMT2ARAB9A
SCHEMBL4526835 0.82 HTT (0.68) HTTALDH1A1MEN1KMT2ARAB9A
SCHEMBL18796190 0.81 HTT (0.66) HTTALDH1A1MEN1KMT2ARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101781257-B Bis- (p-hydroxybenzene) -2,3- benzodiazines of 1,4- and its synthetic method 大连九信精细化工有限公司 2017-04-05 — — CN claimed
CN-119790050-A Oxazole TRPML1 agonists and uses thereof 利布拉医疗公司 2025-04-08 — — CN disclosed
CN-119546588-A Pyridine checkpoint kinase 1 (CHK 1) inhibitors and uses thereof 无界生物公司 2025-02-28 — — CN disclosed
CN-118488945-A Sulfonamide ribonucleotide reductase (RNR) inhibitors and uses thereof 无界生物公司 2024-08-13 — — CN disclosed
CN-118434417-A Cyclic sulfonamide ribonucleotide reductase (RNR) inhibitors and uses thereof 无界生物公司 2024-08-02 — — CN disclosed
CN-116507626-A Compositions and methods for modulating short-chain dehydrogenase activity 罗迪奥治疗公司 2023-07-28 — — CN disclosed
CN-101781257-B Bis- (p-hydroxybenzene) -2,3- benzodiazines of 1,4- and its synthetic method 大连九信精细化工有限公司 2017-04-05 — — CN disclosed
CN-105593714-A Long optical film, circularly polarizing plate provided with long optical film, and organic electroluminescent display device KONICA MINOLTA INC 2016-05-18 — — CN disclosed
US-20160003995-A1 OPTICAL FILM, CIRCULARLY POLARIZING PLATE, AND ORGANIC ELECTROLUMINESCENT DISPLAY DEVICE Konica Minolta, Inc. (JP) 2016-01-07 — — US disclosed
CN-104135859-A Substituted benzaldehyde compounds and methods for their use to increase tissue oxygenation GLOBAL BLOOD THERAPEUTICS INC 2014-11-05 — — CN disclosed
EP-1267819-B1 Quinoxaline derivatives, compositions containing them und use as UV-filter MERCK PATENT GMBH (DE) 2008-08-06 — — EP disclosed
EP-0082699-B1 HERBICIDAL QUINOXALINYL ETHERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1985-11-13 — — EP disclosed
EP-0082699-A1 Herbicidal quinoxalinyl ethers E.I. DU PONT DE NEMOURS AND COMPANY (US) 1983-06-29 — — EP disclosed
EP-0082699-A1 Herbicidal quinoxalinyl ethers E.I. DU PONT DE NEMOURS AND COMPANY (US) 1983-06-29 — — EP disclosed