Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 10/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.66 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11030583 | 0.82 | HTT (0.77) | HTTALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL8880504 | 0.79 | HTT (1.00) | HTTALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL4526835 | 0.78 | HTT (0.68) | HTTALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL9282533 | 0.78 | HTT (0.60) | HTTALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL6002434 | 0.78 | HTT (0.60) | HTTALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL25899364 | 0.78 | HTT (0.55) | HTTALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL10904809 | 0.77 | HTT (0.74) | HTTALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL30534581 | 0.77 | HTT (0.74) | HTTALDH1A1MEN1KMT2ARAB9A | |
| Formaldehyde SCHEMBL28251520 | 0.77 | HTT (0.69) | HTTALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL3151982 | 0.76 | MEN1 (0.65) | HTTALDH1A1MEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0284781-B1 | PROCESS FOR MAKING A 2,3-DIHYDROXYQUINOXALINE | INTEROX Société Anonyme (BE) | 1991-10-16 | — | — | EP | disclosed |
| US-4925941-A | OXIDATION WITH HYDROGEN PEROXIDE, SELENIUM OXIDE CATALYST | INTEROX (SOCIETE ANONYME) (BE) | 1990-05-15 | — | — | US | disclosed |
| EP-0284781-A1 | Process for making a 2,3-dihydroxyquinoxaline | INTEROX Société Anonyme (BE) | 1988-10-05 | — | — | EP | disclosed |