Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2222145 | 0.89 | GAA (0.55) | MEN1KMT2AMAPTGAAKDM4E | |
| SCHEMBL8995858 | 0.84 | GAA (0.51) | MEN1KMT2AMAPTGAAKDM4E | |
| SCHEMBL27867995 | 0.82 | GAA (0.53) | MEN1KMT2AMAPTGAAKDM4E | |
| SCHEMBL28645163 | 0.82 | GAA (0.55) | MEN1KMT2AMAPTGAAKDM4E | |
| SCHEMBL10716248 | 0.81 | KDM4E (0.49) | MEN1KMT2AMAPTGAAKDM4E | |
| SCHEMBL27693696 | 0.81 | LMNA (0.51) | MEN1KMT2AMAPTGAAKDM4E | |
| SCHEMBL8076620 | 0.81 | KDM4E (0.49) | MEN1KMT2AMAPTGAAKDM4E | |
| SCHEMBL12987090 | 0.81 | KDM4E (0.55) | MEN1KMT2AMAPTGAAKDM4E | |
| SCHEMBL12987092 | 0.81 | KDM4E (0.55) | MEN1KMT2AMAPTGAAKDM4E | |
| SCHEMBL23027214 | 0.80 | GAA (0.62) | MEN1KMT2AMAPTGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0055907-B1 | CIS-C3\",C4\"-CARBONATE DERIVATIVES OF OLEANDOMYCIN-Y, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND INTERMEDIATES THEREFOR | PFIZER INC. (US) | 1985-04-10 | — | — | EP | disclosed |
| EP-0055907-A2 | Cis-C3\",C4\"-carbonate derivatives of oleandomycin-Y, pharmaceutical compositions containing them, and intermediates therefor | PFIZER INC. (US) | 1982-07-14 | — | — | EP | disclosed |
| US-4316010-A | BACTERICIDES | PFIZER INC. (US) | 1982-02-16 | — | — | US | disclosed |