Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.50 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | PLAU | P00749 | 1/20 | 0.50 |
| ▸ | ELANE | P08246 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL9177721 | 0.98 | MEN1 (0.57) | MEN1KMT2AALDH1A1HDAC8HDAC6 | |
| SCHEMBL7107935 | 0.83 | ALDH1A1 (0.77) | MEN1KMT2AALDH1A1HDAC8HDAC6 | |
| SCHEMBL8843411 | 0.82 | ALDH1A1 (0.59) | MEN1KMT2AALDH1A1HDAC8HDAC6 | |
| SCHEMBL14647889 | 0.82 | MEN1 (0.65) | MEN1KMT2AALDH1A1HDAC8HDAC6 | |
| SCHEMBL8395080 | 0.81 | ALDH1A1 (0.58) | MEN1KMT2AALDH1A1HDAC8HDAC6 | |
| SCHEMBL5089606 | 0.80 | ALDH1A1 (0.61) | MEN1KMT2AALDH1A1HDAC8HDAC6 | |
| SCHEMBL1095091 | 0.80 | MEN1 (0.61) | MEN1KMT2AALDH1A1HDAC8HDAC6 | |
| SCHEMBL29148895 | 0.79 | MEN1 (0.72) | MEN1KMT2AALDH1A1HDAC8HDAC6 | |
| SCHEMBL14648001 | 0.79 | MEN1 (0.76) | MEN1KMT2AALDH1A1HDAC8HDAC6 | |
| SCHEMBL30078575 | 0.79 | PPID (0.55) | MEN1KMT2AALDH1A1HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0093765-A4 | 2-HYDROXYPROPYLAMINE ARYL ESTER DERIVATIVES. | AMERICAN HOSPITAL SUPPLY CORP (US) | 1984-04-27 | — | — | EP | disclosed |
| EP-0093765-A1 | 2-HYDROXYPROPYLAMINE ARYL ESTER DERIVATIVES. | AMERICAN HOSPITAL SUPPLY CORP (US) | 1983-11-16 | — | — | EP | disclosed |
| WO-1983001770-A1 | 2-HYDROXYPROPYLAMINE ARYL ESTER DERIVATIVES | AMERICAN HOSPITAL SUPPLY CORP (US) | 1983-05-26 | — | — | WO | disclosed |