Tert-Butylamine

Tert-Butylamine

SCHEMBL11031124

C=Cc1ccccc1CC.CC(C)(C)N

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACEIDH1

The experimentally established mechanism targets of Tert-Butylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 2/20 0.39
GABRB2 P47870 2/20 0.39
ALDH1A1 P00352 2/20 0.38
CYP2C19 P33261 1/20 0.37
CCR3 P51677 1/20 0.33
MGLL Q99685 1/20 0.32
SLC6A2 P23975 1/20 0.32
TAAR1 Q96RJ0 1/20 0.32
LOXL2 Q9Y4K0 2/20 0.32
RIPK1 Q13546 2/20 0.32
GAA P10253 1/20 0.32
MAPT P10636 1/20 0.32
CTSB P07858 1/20 0.32
CYP24A1 Q07973 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methylamine SCHEMBL1256495 0.90 ALDH1A1 (0.41) GABRA1GABRB2ALDH1A1CCR3MGLL
SCHEMBL29749448 0.90 ALDH1A1 (0.44) GABRA1GABRB2ALDH1A1CCR3MGLL
SCHEMBL14959 0.90 ALDH1A1 (0.44) GABRA1GABRB2ALDH1A1CCR3MGLL
Ethylamine SCHEMBL11032884 0.88 ALDH1A1 (0.40) GABRA1GABRB2ALDH1A1CCR3MGLL
SCHEMBL6849255 0.88 ALDH1A1 (0.43) GABRA1GABRB2ALDH1A1CCR3MGLL
Water SCHEMBL28085262 0.88 ALDH1A1 (0.43) GABRA1GABRB2ALDH1A1CCR3MGLL
Benzene SCHEMBL9141668 0.88 ALDH1A1 (0.43) GABRA1GABRB2ALDH1A1CCR3MGLL
SCHEMBL9576114 0.88 ALDH1A1 (0.43) GABRA1GABRB2ALDH1A1CCR3MGLL
SCHEMBL28802097 0.88 ALDH1A1 (0.43) GABRA1GABRB2ALDH1A1CCR3MGLL
SCHEMBL8590907 0.86 ALDH1A1 (0.41) GABRA1GABRB2ALDH1A1CCR3MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0052330-B1 NOVEL RESIN COMPOSITION, COATING MATERIAL COMPRISING SAID RESIN COMPOSITION AND METHOD FOR FORMING COATINGS Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1984-09-05 EP claimed
US-4447580-A POLYMER CONSISTING OF UNSATD AROMATIC AMINE AND UNSATURATED COMPOUND WITH ELECTRON ATTRACTIVE GROUP ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1984-05-08 US claimed
EP-0052330-A1 Novel resin composition, coating material comprising said resin composition and method for forming coatings Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1982-05-26 EP claimed
EP-0052330-B1 NOVEL RESIN COMPOSITION, COATING MATERIAL COMPRISING SAID RESIN COMPOSITION AND METHOD FOR FORMING COATINGS Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1984-09-05 EP disclosed
US-4447580-A POLYMER CONSISTING OF UNSATD AROMATIC AMINE AND UNSATURATED COMPOUND WITH ELECTRON ATTRACTIVE GROUP ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1984-05-08 US disclosed
EP-0052330-A1 Novel resin composition, coating material comprising said resin composition and method for forming coatings Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1982-05-26 EP disclosed