SCHEMBL11031209

SCHEMBL11031209

COC(OC)P(=O)(OC)OC

nearest known ligand 0.40

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.40
LMNA P02545 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10784498 0.72 LMNA (0.43) CYP2C19LMNA
SCHEMBL28330102 0.71
SCHEMBL7871737 0.69 LMNA (0.42) CYP2C19LMNA
SCHEMBL2911644 0.69
SCHEMBL11343996 0.69 LMNA (0.42) CYP2C19LMNA
SCHEMBL13081005 0.69
SCHEMBL10831670 0.67 LMNA (0.52) CYP2C19LMNA
SCHEMBL15070669 0.67 CYP2C19 (0.40) CYP2C19LMNA
SCHEMBL8434615 0.67
SCHEMBL8842738 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0050778-B1 PROCESS FOR THE PREPARATION OF PHOSPHONOFORMALDEHYDE-HYDRATE BAYER AG (DE) 1984-06-20 EP disclosed
US-4447367-A Phosphonoformaldehyde, a process for its preparation and its use as an intermediate product for the preparation of medicaments BAYER AKTIENGESELLSCHAFT (DE) 1984-05-08 US disclosed
US-4348332-A Phosphonoformaldehyde, a process for its preparation and its use as an intermediate product for the preparation of medicaments BAYER AKTIENGESELLSCHAFT (DE) 1982-09-07 US disclosed
EP-0050778-A1 Process for the preparation of phosphonoformaldehyde-hydrate BAYER AG (DE) 1982-05-05 EP disclosed