Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.46 |
| ▸ | TOP2A | P11388 | 2/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.41 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.41 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2958200 | 0.99 | CYP4F2 (0.48) | CYP4F2CYP4A11TBXAS1TOP2ACES1 | |
| SCHEMBL2954012 | 0.84 | DAGLA (0.38) | CYP4F2CYP4A11TOP2ACES1KCNH2 | |
| SCHEMBL22120171 | 0.79 | KCNH2 (0.52) | CES1KCNH2DAGLA | |
| SCHEMBL7443875 | 0.79 | CYP4F2 (0.51) | CYP4F2CYP4A11TBXAS1TOP2AKCNH2 | |
| SCHEMBL9440177 | 0.78 | KCNH2 (0.68) | KCNH2 | |
| SCHEMBL2952437 | 0.78 | KCNH2 (0.40) | CYP4F2CYP4A11CES1KCNH2ALDH1A1 | |
| SCHEMBL3884465 | 0.77 | CYP4F2 (0.48) | CYP4F2CYP4A11TBXAS1TOP2ACYSLTR2 | |
| SCHEMBL11032626 | 0.76 | CYP4F2 (0.45) | CYP4F2CYP4A11TBXAS1TOP2AKCNH2 | |
| SCHEMBL6646352 | 0.75 | CYP4F2 (0.56) | CYP4F2CYP4A11TBXAS1CYSLTR2CYSLTR1 | |
| SCHEMBL15821166 | 0.75 | CYP4F2 (0.46) | CYP4F2CYP4A11TBXAS1TOP2ACYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0068386-B1 | SUBSTITUTED IMIDAZO(1,5-A)PYRIDINES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL PREPARATIONS CONTAINING THESE COMPOUNDS | CIBA-GEIGY AG (CH) | 1985-12-18 | — | — | EP | disclosed |