Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.48 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TOP2A | P11388 | 1/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.44 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.42 |
| ▸ | CYP4F11 | Q9HBI6 | 1/20 | 0.42 |
| ▸ | CYP4F12 | Q9HCS2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3886140 | 0.91 | CYP4F2 (0.50) | CYP4F2CYP4A11CYP1A2SMN1; SMN2TOP2A | |
| SCHEMBL15821166 | 0.85 | CYP4F2 (0.46) | CYP4F2CYP4A11CYP1A2ALOX5CYP3A4 | |
| SCHEMBL24259216 | 0.82 | KMT2A (0.47) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL7443875 | 0.81 | CYP4F2 (0.51) | CYP4F2CYP4A11CYP1A2ALOX5CYP3A4 | |
| SCHEMBL1135252 | 0.81 | ALDH1A1 (0.48) | CYP1A2CYP2C9CYP2C19KDM4EALDH1A1 | |
| SCHEMBL7205380 | 0.81 | SMN1; SMN2 (0.47) | CYP1A2CYP2C19SMN1; SMN2TBXAS1ALDH1A1 | |
| SCHEMBL1859504 | 0.79 | CYP1A2 (0.57) | CYP4F2CYP4A11CYP1A2ALOX5CYP3A4 | |
| SCHEMBL10896384 | 0.78 | CYP4F2 (0.50) | CYP4F2CYP4A11CYP1A2SMN1; SMN2TOP2A | |
| SCHEMBL2958200 | 0.78 | CYP4F2 (0.48) | CYP4F2CYP4A11CYP1A2ALOX5CYP3A4 | |
| SCHEMBL20197039 | 0.78 | CYSLTR2 (0.54) | CYP4F2CYP4A11ALOX5SMN1; SMN2TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7511144-B2 | Reverse hydroxamic acid derivatives | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 2009-03-31 | — | — | US | disclosed |
| EP-1431285-B1 | REVERSE HYDROXAMIC ACID DERIVATIVES | KAKEN PHARMA CO LTD (JP) | 2009-01-07 | — | — | EP | disclosed |
| US-20040242928-A1 | Tumor necrosis factor converting enzyme inhibitor; antiarthritic agents; lupus; Crohn's disease; multiple sclerosis; antidiabetic agents; infections;; asthma; skin disorders; anemia | STUDOR S.A. (LU) | 2004-12-02 | — | — | US | disclosed |
| EP-1431285-A1 | REVERSE HYDROXAMIC ACID DERIVATIVES | Kaken Pharmaceutical Co., Ltd. (JP) | 2004-06-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040242928-A1 | Tumor necrosis factor converting enzyme inhibitor; antiarthritic agents; lupus; Crohn's disease; multiple sclerosis; antidiabetic agents; infections;; asthma; skin disorders; anemia | TNF, RNASE1, IFNAR1 | CYP4F2 3224/4885CYP4A11 2163/4885CYP1A2 1130/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.