Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.45 |
| ▸ | MEN1 | O00255 | 7/20 | 0.43 |
| ▸ | MAPT | P10636 | 11/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 6/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ESRRA | P11474 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | CCR6 | P51684 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9132218 | 0.96 | KMT2A (0.44) | KMT2AMEN1MAPTPOLBLMNA | |
| SCHEMBL11030688 | 0.91 | MAPT (0.46) | KMT2AMEN1MAPTPOLBLMNA | |
| SCHEMBL8659316 | 0.88 | ESRRA (0.50) | KMT2AMEN1MAPTPOLBUSP2 | |
| SCHEMBL10961870 | 0.86 | RAB9A (0.49) | KMT2AMEN1MAPTPOLBUSP2 | |
| SCHEMBL11029001 | 0.85 | GCGR (0.53) | KMT2AMEN1MAPTPOLBLMNA | |
| SCHEMBL8657600 | 0.85 | MEN1 (0.52) | KMT2AMEN1MAPTPOLBLMNA | |
| SCHEMBL8661001 | 0.84 | ESRRA (0.48) | KMT2AMEN1MAPTUSP2ALOX15 | |
| SCHEMBL11034061 | 0.84 | NPC1 (0.46) | KMT2AMEN1MAPTUSP2ALOX15 | |
| SCHEMBL11030603 | 0.83 | MEN1 (0.43) | KMT2AMEN1MAPTPOLBUSP2 | |
| SCHEMBL8658967 | 0.83 | NPC1 (0.47) | KMT2AMEN1MAPTPOLBESRRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0124283-A1 | Process for the preparation of benzoyl ureas | UNION CARBIDE CORPORATION (US) | 1984-11-07 | — | — | EP | disclosed |
| US-4426385-A | Insecticidal bicyclooxyphenyl ureas | UNION CARBIDE CORPORATION (US) | 1984-01-17 | — | — | US | disclosed |