SCHEMBL11032057

SCHEMBL11032057

CCCCCSc1[c]nccc1

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 1/20 0.39
SOAT1 P35610 9/20 0.36
TDP1 Q9NUW8 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
PTGS2 P35354 3/20 0.35
TLR8 Q9NR97 1/20 0.35
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
TP53 P04637 1/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19349014 0.80
SCHEMBL310542 0.71 SOAT1 (0.41) GPR84SOAT1PTGS2
SCHEMBL11483337 0.70 SOAT1 (0.42) GPR84SOAT1PTGS2
SCHEMBL2452782 0.70 SOAT1 (0.42) GPR84SOAT1PTGS2
SCHEMBL11111116 0.70 SOAT1 (0.42) GPR84SOAT1PTGS2
SCHEMBL8943722 0.70 SOAT1 (0.42) GPR84SOAT1PTGS2
SCHEMBL8930349 0.70 SOAT1 (0.42) GPR84SOAT1PTGS2
SCHEMBL5495850 0.70 SOAT1 (0.42) GPR84SOAT1PTGS2
SCHEMBL15844402 0.70 SOAT1 (0.42) GPR84SOAT1PTGS2
SCHEMBL239455 0.69 TDP1 (0.46) TDP1L3MBTL1TLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0157712-A1 Arylthio-pyridinyl alcanols RHONE-POULENC AGROCHIMIE (FR) 1985-10-09 EP disclosed