Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4586718 | 0.98 | TDP1 (0.44) | TDP1L3MBTL1KCNH2TRPV1LIPG | |
| SCHEMBL9013118 | 0.98 | TDP1 (0.44) | TDP1L3MBTL1KCNH2TRPV1LIPG | |
| SCHEMBL4584095 | 0.98 | TDP1 (0.44) | TDP1L3MBTL1KCNH2TRPV1LIPG | |
| SCHEMBL4585106 | 0.98 | TDP1 (0.44) | TDP1L3MBTL1KCNH2TRPV1LIPG | |
| SCHEMBL15344545 | 0.98 | TDP1 (0.44) | TDP1L3MBTL1KCNH2TRPV1LIPG | |
| SCHEMBL4584429 | 0.98 | TDP1 (0.44) | TDP1L3MBTL1KCNH2TRPV1LIPG | |
| SCHEMBL4585040 | 0.98 | TDP1 (0.44) | TDP1L3MBTL1KCNH2TRPV1LIPG | |
| SCHEMBL4585397 | 0.98 | TDP1 (0.44) | TDP1L3MBTL1KCNH2TRPV1LIPG | |
| SCHEMBL4586892 | 0.98 | TDP1 (0.44) | TDP1L3MBTL1KCNH2TRPV1LIPG | |
| SCHEMBL695229 | 0.94 | L3MBTL1 (0.39) | TDP1L3MBTL1KCNH2TLR8TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 184 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116836142-A | 3-chromone-2-sulfonyl acrylonitrile derivative and preparation method and application thereof | 广东海洋大学 | 2023-10-03 | — | — | CN | claimed |
| CN-110114438-A | Electrochromic compounds and optical goods containing them | 依视路国际公司 | 2019-08-09 | — | — | CN | claimed |
| CN-109593081-A | A kind of compound for organic photoelectric device and the organic electro-optic device comprising it | 北京绿人科技有限责任公司 | 2019-04-09 | — | — | CN | claimed |
| CN-108948098-A | A kind of metal complex and its application with benzo cycloalkane ligand | 瑞声科技（南京）有限公司 | 2018-12-07 | — | — | CN | claimed |
| EP-2318006-B1 | NOVEL PYRROLE INHIBITORS OF S-NITROSOGLUTATHIONE REDUCTASE AS THERAPEUTIC AGENTS | NIVALIS THERAPEUTICS INC (US) | 2016-10-12 | — | — | EP | claimed |
| CN-103904225-B | A kind of organic electroluminescence device with barrier layer | GU'AN YEOLIGHT TECHNOLOGY CO., LTD. (CN) | 2016-05-25 | — | — | CN | claimed |
| EP-2496579-B1 | 1-SUBSTITUTED 2-AZABICYCLO[3.1.1]HEPTYL DERIVATIVES USEFUL AS NICOTINIC ACETYLCHOLINE RECEPTOR MODULATORS FOR TREATING NEUROLOGIC DISORDERS | UNIV GENT (BE) | 2015-10-21 | — | — | EP | claimed |
| US-9138427-B2 | Pyrrole inhibitors of S-nitrosoglutathione reductase as therapeutic agents | NIVALIS THERAPEUTICS, INC. (US) | 2015-09-22 | — | — | US | claimed |
| US-8900725-B2 | Dendrimer and organic light-emitting device using the same | SAMSUNG DISPLAY CO., LTD. | 2014-12-02 | — | — | US | claimed |
| US-8865322-B2 | Dendrimer and organic light-emitting device using the same | SAMSUNG DISPLAY CO., LTD. (KR) | 2014-10-21 | — | — | US | claimed |
| US-6849643-B2 | Indazolyl-substituted pyrroline compounds as kinase inhibitors | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2005-02-01 | — | — | US | claimed |
| WO-2005000283-A2 | A METHOD OF TREATING DEGENERATIVE DISC DISEASE | DEPUY SPINE, INC. (US) | 2005-01-06 | — | — | WO | claimed |
| CN-1179982-C | Olefine polymerization catalyst, synthesis method and its use | 中国科学院上海有机化学研究所 | 2004-12-15 | — | — | CN | claimed |
| CN-1527835-A | Method for producing highly pure tris-ortho-metalated organoiridium compounds | �����л��뵼������˾ | 2004-09-08 | — | — | CN | claimed |
| US-20040077862-A1 | Method for the production of highly pure, tris-ortho-metalated organo-iridium compounds | MERCK PATENT GMBH (DE) | 2004-04-22 | — | — | US | claimed |
| EP-1366054-A1 | METHOD FOR THE PRODUCTION OF HIGHLY PURE, TRIS-ORTHO-METALATED ORGANO-IRIDIUM COMPOUNDS | Covion Organic Semiconductors GmbH (DE) | 2003-12-03 | — | — | EP | claimed |
| CN-1422874-A | Olefine polymerization catalyst, synthesis method and its use | SHANGHAI INST ORGANIC CHEM (CN) | 2003-06-11 | — | — | CN | claimed |
| WO-2002060910-A1 | METHOD FOR THE PRODUCTION OF HIGHLY PURE, TRIS-ORTHO-METALATED ORGANO-IRIDIUM COMPOUNDS | COVION ORGANIC SEMICONDUCTORS GMBH (DE) | 2002-08-08 | — | — | WO | claimed |
| US-6066641-A | PHOSPHODIESTERASES AS MOLECULAR TARGETS FOR ANTI-ASTHMATIC AGENTS | EURO-CELTIQUE S.A. (LU) | 2000-05-23 | — | — | US | claimed |
| US-5260323-A | 2,4- and 2,5-substituted pyridine-N-oxides, processes for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-09 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040077862-A1 | Method for the production of highly pure, tris-ortho-metalated organo-iridium compounds | CDK8, IPO8, PAX8 | TDP1 2844/4885L3MBTL1 2766/4885KCNH2 495/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.