Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.48 |
| ▸ | RARB | P10826 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5577218 | 0.92 | PPARA (0.48) | GAAL3MBTL1MAPTTP53TSHR | |
| SCHEMBL5577217 | 0.92 | PPARA (0.48) | GAAL3MBTL1MAPTTP53TSHR | |
| SCHEMBL26091436 | 0.88 | GAA (0.54) | GAAL3MBTL1MAPTTP53TSHR | |
| SCHEMBL26088754 | 0.88 | GAA (0.54) | GAAL3MBTL1MAPTTP53TSHR | |
| SCHEMBL1743906 | 0.86 | MAPT (0.53) | GAAL3MBTL1MAPTTP53TSHR | |
| SCHEMBL558993 | 0.86 | MAPT (0.53) | GAAL3MBTL1MAPTTP53TSHR | |
| SCHEMBL26092045 | 0.86 | MAPT (0.53) | GAAL3MBTL1MAPTTP53TSHR | |
| SCHEMBL4538607 | 0.85 | PPARA (0.58) | GAAL3MBTL1MAPTTP53TSHR | |
| SCHEMBL1745096 | 0.85 | PPARA (0.58) | GAAL3MBTL1MAPTTP53TSHR | |
| SCHEMBL20567660 | 0.85 | PPARA (0.58) | GAAL3MBTL1MAPTTP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0111345-A2 | Isoxazoles, useful as antiviral agents, and preparation thereof | STERLING DRUG INC. (US) | 1984-06-20 | — | — | EP | disclosed |
| US-4451476-A | Isoxazoles as antiviral agents | STERLING DRUG INC. (US) | 1984-05-29 | — | — | US | disclosed |