Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | PLA2G4B | P0C869 | 4/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ALB | P02768 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.47 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1745096 | 1.00 | PPARA (0.58) | PPARAGAAPLA2G4BTP53TSHR | |
| SCHEMBL26091641 | 1.00 | PPARA (0.58) | PPARAGAAPLA2G4BTP53TSHR | |
| SCHEMBL2183439 | 1.00 | PPARA (0.58) | PPARAGAAPLA2G4BTP53TSHR | |
| SCHEMBL4540684 | 1.00 | PPARA (0.58) | PPARAGAAPLA2G4BTP53TSHR | |
| SCHEMBL4538607 | 1.00 | PPARA (0.58) | PPARAGAAPLA2G4BTP53TSHR | |
| SCHEMBL557204 | 1.00 | PPARA (0.58) | PPARAGAAPLA2G4BTP53TSHR | |
| SCHEMBL1363883 | 0.92 | PPARA (0.51) | PPARAGAAPLA2G4BTP53TSHR | |
| SCHEMBL28155239 | 0.86 | PPARA (0.56) | PPARAGAAPLA2G4BTP53TSHR | |
| SCHEMBL1743906 | 0.86 | MAPT (0.53) | GAATP53TSHRL3MBTL1HDAC1 | |
| SCHEMBL558993 | 0.86 | MAPT (0.53) | GAATP53TSHRL3MBTL1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4419540-A1 | IMMUNOMODULATORS | Bristol-Myers Squibb Company (US) | 2024-08-28 | — | — | EP | disclosed |
| CN-118159549-A | Immunomodulators | 百时美施贵宝公司 | 2024-06-07 | — | — | CN | disclosed |
| US-20230364248-A1 | MIC-1 COMPOUNDS AND USES THEREOF | NOVO NORDISK AS (DK) | 2023-11-16 | — | — | US | disclosed |
| WO-2023069994-A1 | IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-04-27 | — | — | WO | disclosed |
| WO-2023069994-A1 | IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-04-27 | — | — | WO | disclosed |
| CN-111183148-A | MIC-1 compounds and uses thereof | 诺和诺德股份有限公司 | 2020-05-19 | — | — | CN | disclosed |
| EP-3630805-A1 | MIC-1 COMPOUNDS AND USES THEREOF | Novo Nordisk A/S (DK) | 2020-04-08 | — | — | EP | disclosed |
| US-20200079829-A1 | MIC-1 COMPOUNDS AND USES THEREOF | NOVO NORDISK A/S (DK) | 2020-03-12 | — | — | US | disclosed |
| US-10398782-B2 | MIC-1 compounds and uses thereof | NOVO NORDISK A/S (DK) | 2019-09-03 | — | — | US | disclosed |
| WO-2018215525-A1 | MIC-1 COMPOUNDS AND USES THEREOF | NOVO NORDISK A/S (DK) | 2018-11-29 | — | — | WO | disclosed |
| US-20180339057-A1 | MIC-1 Compounds and Uses Thereof | NOVO NORDISK A/S (DK) | 2018-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200079829-A1 | MIC-1 COMPOUNDS AND USES THEREOF | IMMT, MICA, TAP1 | PPARA 2549/4885GAA 3121/4885PLA2G4B 4779/4885 |
| US-10398782-B2 | MIC-1 compounds and uses thereof | IMMT, MICA, TAP1 | PPARA 2549/4885GAA 3121/4885PLA2G4B 4779/4885 |
| US-20230364248-A1 | MIC-1 COMPOUNDS AND USES THEREOF | IMMT, MICA, TAP1 | PPARA 2549/4885GAA 3121/4885PLA2G4B 4779/4885 |
| US-20180339057-A1 | MIC-1 Compounds and Uses Thereof | IMMT, MICA, TAP1 | PPARA 2549/4885GAA 3121/4885PLA2G4B 4779/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.