SCHEMBL11032287

SCHEMBL11032287

CC1CC(C(=O)O)N(C=O)C1

nearest known ligand 0.42

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.40
KMT2A Q03164 2/20 0.37
MEN1 O00255 1/20 0.30
HPGD P15428 1/20 0.30
PLA2G1B P04054 1/20 0.30
ATG4B Q9Y4P1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8337707 0.82 ATM (0.50) ATMKMT2A
SCHEMBL14365837 0.82 ATM (0.50) ATMKMT2A
SCHEMBL17428805 0.78 KMT2A (0.34) ATMKMT2A
SCHEMBL16855020 0.76 KMT2A (0.33) ATMKMT2A
SCHEMBL9361472 0.75 ATM (0.42) ATMKMT2A
SCHEMBL27985023 0.74 ATM (0.45) ATMKMT2AMEN1HPGDPLA2G1B
SCHEMBL24354973 0.72 ATM (0.44) ATMPLA2G1BATG4B
SCHEMBL10330907 0.72 ATM (0.44) ATMPLA2G1BATG4B
SCHEMBL4072231 0.72 ATM (0.44) ATMPLA2G1BATG4B
SCHEMBL13164365 0.72 ATM (0.44) ATMPLA2G1BATG4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1982000402-A1 HERBICIDAL AND PLANT GROWTH REGULANT DIPHENYLPYRIDAZINONES DIAMOND SHAMROCK CORP (US) 1982-02-18 WO claimed
EP-0046069-A1 Herbicidal and plant growth regulant diphenylpyridazinones DIAMOND SHAMROCK CORPORATION (US) 1982-02-17 EP claimed
US-4545810-A Herbicidal and plant growth regulant diphenylpyridazinones SDS BIOTECH CORPORATION (US) 1985-10-08 US disclosed
WO-1982000402-A1 HERBICIDAL AND PLANT GROWTH REGULANT DIPHENYLPYRIDAZINONES DIAMOND SHAMROCK CORP (US) 1982-02-18 WO disclosed
EP-0046069-A1 Herbicidal and plant growth regulant diphenylpyridazinones DIAMOND SHAMROCK CORPORATION (US) 1982-02-17 EP disclosed