SCHEMBL11032669

SCHEMBL11032669

CCCSP(=O)(OCC)Oc1ccc(C(=C(Cl)Cl)c2ccc(OP(=O)(OCC)SCCC)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
BLM P54132 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
BCHE P06276 1/20 0.36
ACHE P22303 1/20 0.36
ALDH1A1 P00352 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10675535 0.95 ALDH1A1 (0.37) ACHEALDH1A1
SCHEMBL11033859 0.85 KMT2A (0.43) BLMCA1CA2BCHEACHE
Butane SCHEMBL11031560 0.84 KMT2A (0.42) BLMCA1CA2BCHEACHE
SCHEMBL10999297 0.82 MEN1 (0.46) CA1CA2BCHEACHE
SCHEMBL11737398 0.81 ALDH1A1 (0.41) ALDH1A1
Methoxymethane SCHEMBL11034001 0.80 BLM (0.35) BLMCA1CA2BCHEACHE
SCHEMBL11033998 0.80 MAPT (0.36) BLMCA1CA2BCHEACHE
SCHEMBL11034196 0.79 CA1 (0.37) CA1CA2BCHEACHE
SCHEMBL11031581 0.79 CYP2C19 (0.37) CA1CA2BCHEACHE
SCHEMBL11033364 0.79 CA1 (0.37) CA1CA2BCHEACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4457922-A INSECTICIDES, MITICIDES UNION CARBIDE CORPORATION (US) 1984-07-03 US disclosed