SCHEMBL11032702

SCHEMBL11032702

CCCCCc1ccc(-c2ccc(OCCCC)cc2)c(C#N)c1C#N

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.46
KDM4E B2RXH2 5/20 0.46
HPGD P15428 5/20 0.46
L3MBTL1 Q9Y468 3/20 0.46
HTT P42858 1/20 0.46
MAPT P10636 3/20 0.45
HSD17B10 Q99714 2/20 0.44
TSHR P16473 1/20 0.44
CYP3A4 P08684 4/20 0.43
LMNA P02545 2/20 0.43
MEN1 O00255 2/20 0.43
USP2 O75604 2/20 0.43
KMT2A Q03164 2/20 0.43
MAPK1 P28482 1/20 0.43
CASP1 P29466 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
SLCO1B3 Q9NPD5 1/20 0.43
SLCO1B1 Q9Y6L6 1/20 0.43
CYP2D6 P10635 2/20 0.41
CNR2 P34972 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11032313 0.99 ALDH1A1 (0.48) ALDH1A1KDM4EHPGDL3MBTL1HTT
SCHEMBL11031091 0.99 ALDH1A1 (0.48) ALDH1A1KDM4EHPGDL3MBTL1HTT
SCHEMBL11033942 0.97 ALDH1A1 (0.44) ALDH1A1KDM4EHPGDL3MBTL1HTT
SCHEMBL11033373 0.97 ALDH1A1 (0.50) ALDH1A1KDM4EHPGDL3MBTL1HTT
SCHEMBL11031027 0.97 ALDH1A1 (0.50) ALDH1A1KDM4EHPGDL3MBTL1HTT
SCHEMBL11035279 0.97 ALDH1A1 (0.50) ALDH1A1KDM4EHPGDL3MBTL1HTT
SCHEMBL11033881 0.97 ALDH1A1 (0.50) ALDH1A1KDM4EHPGDL3MBTL1HTT
SCHEMBL11034096 0.96 ALDH1A1 (0.46) ALDH1A1KDM4EHPGDL3MBTL1HTT
SCHEMBL10579399 0.96 TSHR (0.45) ALDH1A1KDM4EHPGDL3MBTL1HTT
SCHEMBL11031878 0.96 ALDH1A1 (0.46) ALDH1A1KDM4EHPGDL3MBTL1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4479885-A Phthalonitrile derivatives and a liquid crystal composition containing the same HITACHI, LTD. (JP) 1984-10-30 US disclosed
EP-0087963-A2 Phthalonitrile derivatives and liquid crystal compositions containing them Hitachi, Ltd. (JP) 1983-09-07 EP disclosed