Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | GMNN | O75496 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | THPO | P40225 | 1/20 | 0.53 |
| ▸ | MTOR | P42345 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | CETP | P11597 | 1/20 | 0.53 |
| ▸ | UBE2N | P61088 | 1/20 | 0.53 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5652970 | 0.96 | SPHK1 (0.52) | SPHK1CYP2D6LMNAHTTGMNN | |
| SCHEMBL8298974 | 0.89 | SPHK1 (0.50) | SPHK1CYP2D6LMNAHTTGMNN | |
| SCHEMBL14419885 | 0.89 | SPHK1 (0.50) | SPHK1CYP2D6LMNAHTTGMNN | |
| SCHEMBL8652229 | 0.86 | SPHK1 (0.60) | SPHK1CYP2D6LMNAHTTGMNN | |
| SCHEMBL4169780 | 0.86 | SPHK1 (0.60) | SPHK1CYP2D6LMNAHTTGMNN | |
| SCHEMBL17501649 | 0.86 | SPHK1 (0.60) | SPHK1CYP2D6LMNAHTTGMNN | |
| SCHEMBL751283 | 0.86 | SPHK1 (0.60) | SPHK1CYP2D6LMNAHTTGMNN | |
| SCHEMBL3730643 | 0.86 | SPHK1 (0.60) | SPHK1CYP2D6LMNAHTTGMNN | |
| SCHEMBL8517654 | 0.86 | SPHK1 (0.60) | SPHK1CYP2D6LMNAHTTGMNN | |
| SCHEMBL29879550 | 0.86 | SPHK1 (0.60) | SPHK1CYP2D6LMNAHTTGMNN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0054430-B1 | TERTIARY AMINO POLYOLS | HENKEL CORPORATION (a Delaware corp.) (US) | 1985-03-13 | — | — | EP | disclosed |
| US-4413138-A | Glycidyl ethers of aminopolyols | HENKEL CORPORATION (US) | 1983-11-01 | — | — | US | disclosed |
| EP-0054430-A1 | Tertiary amino polyols | HENKEL CORPORATION (a Delaware corp.) (US) | 1982-06-23 | — | — | EP | disclosed |
| US-4328371-A | USEFUL IN THE PRODUCTION OF POLYURETHANES | HENKEL CORPORATION (US) | 1982-05-04 | — | — | US | disclosed |