Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | GMNN | O75496 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | THPO | P40225 | 1/20 | 0.56 |
| ▸ | MTOR | P42345 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | CETP | P11597 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | UBE2N | P61088 | 1/20 | 0.56 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL180470 | 1.00 | SPHK1 (0.60) | SPHK1CYP2D6LMNAGMNNPOLB | |
| SCHEMBL27970625 | 1.00 | SPHK1 (0.60) | SPHK1CYP2D6LMNAGMNNPOLB | |
| SCHEMBL27612145 | 1.00 | SPHK1 (0.60) | SPHK1CYP2D6LMNAGMNNPOLB | |
| SCHEMBL29879550 | 1.00 | SPHK1 (0.60) | SPHK1CYP2D6LMNAGMNNPOLB | |
| SCHEMBL8517654 | 1.00 | SPHK1 (0.60) | SPHK1CYP2D6LMNAGMNNPOLB | |
| SCHEMBL3730643 | 1.00 | SPHK1 (0.60) | SPHK1CYP2D6LMNAGMNNPOLB | |
| SCHEMBL751283 | 1.00 | SPHK1 (0.60) | SPHK1CYP2D6LMNAGMNNPOLB | |
| SCHEMBL8652229 | 1.00 | SPHK1 (0.60) | SPHK1CYP2D6LMNAGMNNPOLB | |
| SCHEMBL17501649 | 1.00 | SPHK1 (0.60) | SPHK1CYP2D6LMNAGMNNPOLB | |
| SCHEMBL27243094 | 0.97 | SPHK1 (0.58) | SPHK1CYP2D6LMNAGMNNPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1996514-B1 | REMOVAL OF SKIN CHANGES | GALIC BORIVOJ (BA) | 2013-07-31 | — | — | EP | disclosed |
| US-8278289-B2 | Boroxine composition for removal of skin changes | GALIC, ZORAN (BA) | 2012-10-02 | — | — | US | disclosed |
| US-20090238897-A1 | REMOVAL OF SKIN CHANGES | GALIC, TATJANA (BA) | 2009-09-24 | — | — | US | disclosed |
| EP-1996514-A1 | REMOVAL OF SKIN CHANGES | Galic, Borivoj (BA) | 2008-12-03 | — | — | EP | disclosed |
| WO-2007107809-A1 | REMOVAL OF SKIN CHANGES | GALIC BORIVOJ (BA) | 2007-09-27 | — | — | WO | disclosed |
| EP-0976389-B1 | Solid cosmetic composition | SHISEIDO CO LTD (JP) | 2006-07-19 | — | — | EP | disclosed |
| EP-0976388-B1 | External-use composition | SHISEIDO CO LTD (JP) | 2006-06-14 | — | — | EP | disclosed |
| EP-0701810-B1 | Skin-colour adjusting method, and coloured titanium oxide coated mica used therefor | SHISEIDO CO LTD (JP) | 2004-11-17 | — | — | EP | disclosed |
| US-6509025-B2 | Compacting powders; compression molding; controlling particle sizes | SHISEIDO COMPANY, LTD. (JP) | 2003-01-21 | — | — | US | disclosed |
| US-20020168390-A1 | Method of producing an impact resistant solid cosmetic composition | SHISEIDO COMPANY, LTD. (JP) | 2002-11-14 | — | — | US | disclosed |
| US-6428795-B2 | Skin treatment composition | SHISEIDO COMPANY, LTD. (JP) | 2002-08-06 | — | — | US | disclosed |
| US-20020028221-A1 | SOLID COSMETIC COMPOSITION | SHISEIDO COMPANY, LTD. (JP) | 2002-03-07 | — | — | US | disclosed |
| US-20010007672-A1 | EXTERNAL-USE COMPOSITION | SHISEIDO CO., LTD | 2001-07-12 | — | — | US | disclosed |
| EP-0976389-A1 | Solid cosmetic composition | SHISEIDO COMPANY LIMITED (JP) | 2000-02-02 | — | — | EP | disclosed |
| EP-0976388-A2 | External-use composition | SHISEIDO COMPANY LIMITED (JP) | 2000-02-02 | — | — | EP | disclosed |
| US-5690916-A | TO MAKE HYPERCHROMIC PORTION OF SKIN INCONSPICUOUS DUE TO INTERFERENCE ACTION; BLEMISH CONCEALING COSMETICS | SHISEIDO CO., LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| EP-0701810-A1 | Skin-colour adjusting method, skin-colour adjusting composition, and coloured titanium oxide coated mica used therefor | SHISEIDO COMPANY LIMITED (JP) | 1996-03-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090238897-A1 | REMOVAL OF SKIN CHANGES | BROX, NISCH, BRCA1 | SPHK1 972/4885CYP2D6 3264/4885LMNA 431/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.