Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 6/20 | 0.36 |
| ▸ | BCHE | P06276 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CCR3 | P51677 | 1/20 | 0.35 |
| ▸ | CTSD | P07339 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10917400 | 0.98 | SIGMAR1 (0.46) | SIGMAR1NPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL10917391 | 0.79 | SIGMAR1 (0.49) | SIGMAR1NPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL10920358 | 0.79 | SIGMAR1 (0.49) | SIGMAR1NPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL11034098 | 0.79 | SIGMAR1 (0.49) | SIGMAR1NPC1HPGDRAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10916290 | 0.78 | SIGMAR1 (0.47) | SIGMAR1NPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL10915863 | 0.76 | SIGMAR1 (0.45) | SIGMAR1NPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL10916617 | 0.76 | SIGMAR1 (0.45) | SIGMAR1NPC1HPGDRAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10919365 | 0.75 | SIGMAR1 (0.44) | SIGMAR1NPC1HPGDRAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10920364 | 0.75 | SIGMAR1 (0.44) | SIGMAR1NPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL10918089 | 0.74 | SIGMAR1 (0.43) | SIGMAR1NPC1HPGDRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482547-A | HYPOTENSIVE AGENTS | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1984-11-13 | — | — | US | claimed |