Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.76 |
| ▸ | HPGD | P15428 | 1/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | TP53 | P04637 | 2/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Triethylene Glycol SCHEMBL2819413 | 0.95 | TSHR (0.69) | TSHRHPGDALDH1A1TP53HIF1A | |
| Tetraethylene Glycol SCHEMBL5688428 | 0.95 | TSHR (0.69) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL8621998 | 0.95 | TSHR (0.68) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL9578389 | 0.95 | TSHR (0.68) | TSHRHPGDALDH1A1TP53HIF1A | |
| Tetraethylene Glycol SCHEMBL5808682 | 0.93 | TSHR (0.66) | TSHRHPGDALDH1A1TP53HIF1A | |
| Di(Hydroxyethyl)Ether SCHEMBL6112701 | 0.93 | TSHR (0.71) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL14655594 | 0.92 | TSHR (0.68) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL8419313 | 0.91 | TSHR (0.72) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL1088660 | 0.91 | TSHR (0.85) | TSHRHPGDALDH1A1TP53HIF1A | |
| Butane SCHEMBL6479816 | 0.89 | TSHR (0.70) | TSHRHPGDALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-59021544-A | — | — | None | — | — | JP | disclosed |
| JP-S5921544-A | COATING MATERIAL FOR OPTICAL GLASS FIBER | NITTO ELECTRIC IND CO LTD | 1984-02-03 | — | — | JP | disclosed |